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Annotation rule MF_01001
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General rule information [?]

Accession MF_01001
Dates 7-FEB-2002 (Created)
3-NOV-2020 (Last updated, Version 24)
Name WecG_RffM
Bacteria; Enterobacterales
Template P27836 (WECG_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=UDP-N-acetyl-D-mannosaminuronic acid transferase;
Short=UDP-ManNAcA transferase;
Gene name
wecG, rffM

Comments [?]

Function Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
Catalytic activity RHEA:28366: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosaminouronate = beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP
Pathway Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Similarity Belongs to the glycosyltransferase 26 family.

Keywords [?]

Gene Ontology [?]

GO:0047241; Molecular function: lipopolysaccharide N-acetylmannosaminouronosyltransferase activity.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.

Cross-references [?]

Pfam PF03808; Glyco_tran_WecB; 1;
TIGRFAMs TIGR00696; WecB_tagA_cpsF; 1;

Additional information [?]

Size range 235-260 amino acids
Related rules None
Fusion None