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| Annotation rule MF_01001 |
General rule information
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| Accession | MF_01001 |
| Dates | 7-FEB-2002 (Created) 19-NOV-2019 (Last updated, Version 23) |
| Name | WecG_RffM |
| Scope | Bacteria; Enterobacterales |
| Template | P27836 (WECG_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. |
| Catalytic activity | RHEA:28366: N-acetyl-alpha-D-glucosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + UDP-N-acetyl-alpha-D-mannosaminouronate = beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-di-trans,octa-cis-undecaprenol + H(+) + UDP
EC 2.4.1.180 |
| Pathway | Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis. |
| Similarity | Belongs to the glycosyltransferase 26 family. |
Keywords
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Gene Ontology
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GO:0047241; Molecular function: lipopolysaccharide N-acetylmannosaminouronosyltransferase activity.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
Cross-references
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Additional information
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| Size range | 235-260 amino acids |
| Related rules | None |
| Fusion | None |