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Annotation rule MF_01002 |
Accession | MF_01002 |
Dates | 7-FEB-2002 (Created) 3-NOV-2020 (Last updated, Version 30) |
Name | WecF_RffT |
Scope | Bacteria; Enterobacterales |
Template | P56258 (WECF_ECOLI) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis. |
Catalytic activity | RHEA:28759: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose = alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)
EC 2.4.1.325 |
Pathway | Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis. |
Subcellular location | Cell inner membrane; Peripheral membrane protein. |
Similarity | Belongs to the glycosyltransferase 56 family. |
Pfam | PF07429; Glyco_transf_56; 1; |
Size range | 359-361 amino acids |
Related rules | None |
Fusion | None |