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Annotation rule MF_01002
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General rule information [?]

Accession MF_01002
Dates 7-FEB-2002 (Created)
3-NOV-2020 (Last updated, Version 30)
Name WecF_RffT
Scope
Bacteria; Enterobacterales
Template P56258 (WECF_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
WECF
Protein name
RecName: Full=TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase;
EC 2.4.1.325;
AltName: Full=4-alpha-L-fucosyltransferase;
AltName: Full=TDP-Fuc4NAc:lipid II Fuc4NAc transferase;
Short=Fuc4NAc transferase;
Gene name
wecF, rffT

Comments [?]

Function Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
Catalytic activity RHEA:28759: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose = alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)
EC 2.4.1.325
Pathway Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Subcellular location Cell inner membrane; Peripheral membrane protein.
Similarity Belongs to the glycosyltransferase 56 family.

Keywords [?]

Transferase
Glycosyltransferase
Membrane
Cell membrane
Cell inner membrane

Gene Ontology [?]

GO:0016758; Molecular function: transferase activity, transferring hexosyl groups.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF07429; Glyco_transf_56; 1;

Additional information [?]

Size range 359-361 amino acids
Related rules None
Fusion None


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