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HAMAP rule MF_01005

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General rule information [?]

Accession MF_01005
Dates 15-FEB-2002 (Created)
19-NOV-2022 (Last updated, Version 41)
Name BtuD
Scope
Bacteria; Enterobacterales
Bacteria; Vibrionaceae
Template P06611 (BTUD_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
BTUD
Protein name
RecName: Full=Vitamin B12 import ATP-binding protein BtuD;
EC 7.6.2.8;
AltName: Full=Vitamin B12-transporting ATPase;
Gene name
btuD

Comments [?]

Function Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:17873: an R-cob(III)alamin(out) + ATP + H2O = ADP + an R-cob(III)alamin(in) + H(+) + phosphate
EC 7.6.2.8
Subunit The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Peripheral membrane protein.
end case
Similarity Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Translocase
Transport

Gene Ontology [?]

GO:0015420; Molecular function: ABC-type vitamin B12 transporter activity.
GO:0015889; Biological process: cobalamin transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

Features [?]

From: BTUD_ECOLI (P06611)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     33     40       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-P-N-G-[ASC]-G-K-S  

Additional information [?]

Size range 249-255 amino acids
Related rules None
Fusion None


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