HAMAP rule MF_01005
General rule information
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Accession | MF_01005 |
Dates | 15-FEB-2002 (Created) 19-NOV-2022 (Last updated, Version 41) |
Name | BtuD |
Scope | Bacteria; Enterobacterales
Bacteria; Vibrionaceae |
Template | P06611 (BTUD_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. |
Catalytic activity | RHEA:17873: an R-cob(III)alamin(out) + ATP + H2O = ADP + an R-cob(III)alamin(in) + H(+) + phosphate
EC 7.6.2.8 |
Subunit | The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Peripheral membrane protein. |
end case
Similarity | Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0015420; Molecular function: ABC-type vitamin B12 transporter activity.
GO:0015889; Biological process: cobalamin transport.
GO:0005886; Cellular component: plasma membrane.
GO:0015889; Biological process: cobalamin transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF00005; ABC_tran; 1; |
PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434; |
Features
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From: BTUD_ECOLI (P06611) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 33 | 40 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-P-N-G-[ASC]-G-K-S |
Additional information
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Size range | 249-255 amino acids |
Related rules | None |
Fusion | None |