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| Annotation rule MF_01005 |
General rule information
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| Accession | MF_01005 |
| Dates | 15-FEB-2002 (Created) 13-JAN-2021 (Last updated, Version 38) |
| Name | BtuD |
| Scope | Bacteria; Enterobacterales
Bacteria; Vibrionaceae |
| Template | P06611 (BTUD_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. |
| Catalytic activity | RHEA:17873: ATP + cob(III)alamin(out) + H2O = ADP + cob(III)alamin(in) + H(+) + phosphate
EC 7.6.2.8 |
| Subunit | The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). |
case not defined <Property:Membrane> or <Property:Membrane=1>
| Subcellular location | Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2>
| Subcellular location | Cell inner membrane; Peripheral membrane protein. |
end case
| Similarity | Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0015420; Molecular function: ABC-type vitamin B12 transporter activity.
GO:0015889; Biological process: cobalamin transport.
GO:0005886; Cellular component: plasma membrane.
GO:0015889; Biological process: cobalamin transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434; |
Features
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| From: BTUD_ECOLI (P06611) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| NP_BIND | 33 | 40 | ATP | G-P-N-G-[ASC]-G-K-S | ||||||||
Additional information
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| Size range | 249-255 amino acids |
| Related rules | None |
| Fusion | None |