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Annotation rule MF_01010
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General rule information [?]

Accession MF_01010
Dates 25-MAR-2002 (Created)
19-NOV-2019 (Last updated, Version 29)
Name 23SrRNA_methyltr_RlmD
Bacteria; Proteobacteria
Template P55135 (RLMD_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
AltName: Full=23S rRNA(m5U1939)-methyltransferase;
Gene name

Comments [?]

Function Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
Catalytic activity RHEA:42908: S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0070041; Molecular function: rRNA (uridine-C5-)-methyltransferase activity.
case <FTGroup:1>
GO:0005506; Molecular function: iron ion binding.
end case
GO:0031167; Biological process: rRNA methylation.

Cross-references [?]

Pfam PF01938; TRAM; 1;
PF05958; tRNA_U5-meth_tr; 1;
TIGRFAMs TIGR00479; RumA; 1;
PS50926; TRAM; 0-1; trigger=PRU00208;
PS01230; TRMA_1; 1;
PS01231; TRMA_2; 1;

Features [?]

From: RLMD_ECOLI (P55135)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     389     389       Nucleophile     C  
METAL     81     81       Iron-sulfur (4Fe-4S)     C   1
METAL     87     87       Iron-sulfur (4Fe-4S)     C   1
METAL     90     90       Iron-sulfur (4Fe-4S)     C   1
METAL     162     162       Iron-sulfur (4Fe-4S)     C   1
BINDING     265     265       S-adenosyl-L-methionine     Q  
BINDING     294     294       S-adenosyl-L-methionine; via carbonyl oxygen     F  
BINDING     299     299       S-adenosyl-L-methionine     N  
BINDING     315     315       S-adenosyl-L-methionine     E  
BINDING     342     342       S-adenosyl-L-methionine     [ND]  
BINDING     363     363       S-adenosyl-L-methionine     D  

Additional information [?]

Size range 431-514 amino acids
Related rules MF_01011 (TRMA)
Fusion None