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| Annotation rule MF_01020 |
General rule information
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| Accession | MF_01020 |
| Dates | 24-MAY-2002 (Created) 19-NOV-2019 (Last updated, Version 35) |
| Name | HisE |
| Scope | Bacteria
Archaea |
| Template | P06989 (HIS2_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Catalytic activity | RHEA:22828: 1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)
EC 3.6.1.31 |
| Pathway | Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the PRA-PH family. |
Keywords
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Gene Ontology
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GO:0004636; Molecular function: phosphoribosyl-ATP diphosphatase activity.
GO:0000105; Biological process: histidine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0000105; Biological process: histidine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Additional information
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| Size range | 87-160 amino acids |
| Related rules | MF_01019 (HIS2 supersedes the current rule) |
| Fusion | None |
| Comments | See MF_01019 for the entry relevant to the fused hisI-hisE |