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Annotation rule MF_01031
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General rule information [?]

Accession MF_01031
Dates 6-SEP-2002 (Created)
19-NOV-2019 (Last updated, Version 29)
Name LeuD_type1
Scope
Bacteria
Template P04787 (LEUD1_SALTY)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
LEUD
Protein name
RecName: Full=3-isopropylmalate dehydratase small subunit;
EC 4.2.1.33;
AltName: Full=Alpha-IPM isomerase;
Short=IPMI;
AltName: Full=Isopropylmalate isomerase;
Gene name
leuD

Comments [?]

Function Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Catalytic activity RHEA:32287: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate
EC 4.2.1.33
Pathway Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.
Subunit Heterodimer of LeuC and LeuD.
Similarity Belongs to the LeuD family. LeuD type 1 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003861; Molecular function: 3-isopropylmalate dehydratase activity.
GO:0009098; Biological process: leucine biosynthetic process.

Cross-references [?]

Pfam PF00694; Aconitase_C; 1;
TIGRFAMs TIGR00171; LeuD; 1;

Additional information [?]

Size range 189-230 amino acids
Related rules MF_01032 (HACB)
Fusion None