HAMAP rule MF_01031
General rule information
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Accession | MF_01031 |
Dates | 6-SEP-2002 (Created) 19-NOV-2019 (Last updated, Version 29) |
Name | LeuD_type1 |
Scope | Bacteria |
Template | P04787 (LEUD1_SALTY) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. |
Catalytic activity | RHEA:32287: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate
EC 4.2.1.33 |
Pathway | Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4. |
Subunit | Heterodimer of LeuC and LeuD. |
Similarity | Belongs to the LeuD family. LeuD type 1 subfamily. |
Keywords
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Gene Ontology
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GO:0003861; Molecular function: 3-isopropylmalate dehydratase activity.
GO:0009098; Biological process: leucine biosynthetic process.
GO:0009098; Biological process: leucine biosynthetic process.
Cross-references
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Additional information
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Size range | 189-230 amino acids |
Related rules | MF_01032 (HACB) |
Fusion | None |