HAMAP rule MF_01031

General rule information [?]

Accession	MF_01031
Dates	6-SEP-2002 (Created) 19-NOV-2019 (Last updated, Version 29)

Name	LeuD_type1

Scope

Bacteria

Template

P04787 (LEUD1_SALTY)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

LEUD

Protein name

RecName:		Full=3-isopropylmalate dehydratase small subunit;
		EC 4.2.1.33;
AltName:		Full=Alpha-IPM isomerase;
		Short=IPMI;
AltName:		Full=Isopropylmalate isomerase;

Gene name

leuD

Comments [?]

Function	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Catalytic activity	RHEA:32287: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate EC 4.2.1.33
Pathway	Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.
Subunit	Heterodimer of LeuC and LeuD.
Similarity	Belongs to the LeuD family. LeuD type 1 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003861; Molecular function: 3-isopropylmalate dehydratase activity.
GO:0009098; Biological process: leucine biosynthetic process.

Cross-references [?]

Pfam	PF00694; Aconitase_C; 1;
TIGRFAMs	TIGR00171; LeuD; 1;

Additional information [?]