HAMAP rule MF_01034
General rule information
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Accession | MF_01034 |
Dates | 20-SEP-2002 (Created)
29-SEP-2022 (Last updated, Version 25) |
Name | S12_YfeW |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P77619 (YFEW_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01034 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | YFEW |
Protein name | RecName: Full=Putative D-alanyl-D-alanine carboxypeptidase; EC=3.4.16.4; AltName: Full=DD-carboxypeptidase; Short=DD-CPase; |
Gene name | Name=yfeW; |
Comments
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CATALYTIC ACTIVITY | Reaction=Preferential cleavage: (Ac)2-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.; EC=3.4.16.4; |
SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
SIMILARITY | Belongs to the peptidase S12 family. YfeW subfamily. |
Keywords
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Carboxypeptidase |
Cell inner membrane |
Cell membrane |
Hydrolase |
Membrane |
Protease |
Transmembrane |
Transmembrane helix |
Gene Ontology
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GO:0009002; Molecular function:serine-type D-Ala-D-Ala carboxypeptidase activity |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF00144; Beta-lactamase; 1; |
Features
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From: YFEW_ECOLI (P77619) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 7 | 25 | /note="Helical; Signal-anchor" |
Additional information
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Size range | 420-470 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |