HAMAP rule MF_01034
General rule information
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| Accession | MF_01034 |
| Dates | 20-SEP-2002 (Created)
29-SEP-2022 (Last updated, Version 25) |
| Name | S12_YfeW |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P77619 (YFEW_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01034 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | YFEW |
| Protein name | RecName: Full=Putative D-alanyl-D-alanine carboxypeptidase; EC=3.4.16.4; AltName: Full=DD-carboxypeptidase; Short=DD-CPase; |
| Gene name | Name=yfeW; |
Comments
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| CATALYTIC ACTIVITY | Reaction=Preferential cleavage: (Ac)2-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.; EC=3.4.16.4; |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| SIMILARITY | Belongs to the peptidase S12 family. YfeW subfamily. |
Keywords
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| Carboxypeptidase |
| Cell inner membrane |
| Cell membrane |
| Hydrolase |
| Membrane |
| Protease |
| Transmembrane |
| Transmembrane helix |
Gene Ontology
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| GO:0009002; Molecular function:serine-type D-Ala-D-Ala carboxypeptidase activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF00144; Beta-lactamase; 1; |
Features
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| From: YFEW_ECOLI (P77619) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TRANSMEM | 7 | 25 | /note="Helical; Signal-anchor" | |||||||||
Additional information
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| Size range | 420-470 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |