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Annotation rule MF_01037 |
Accession | MF_01037 |
Dates | 28-NOV-2002 (Created) 27-FEB-2020 (Last updated, Version 30) |
Name | TrmFO |
Scope | Bacteria |
Templates | P39815 (TRMFO_BACSU); Q9S449 (TRMFO_MYXXD): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs. |
Catalytic activity | RHEA:16873: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+)
EC 2.1.1.74 |
RHEA:62372: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)
EC 2.1.1.74 |
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Cofactor | FAD |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the MnmG family. TrmFO subfamily. |
Pfam | PF01134; GIDA; 1; |
TIGRFAMs | TIGR00137; Gid_trmFO; 1; |
PROSITE | PS01280; GIDA_1; 1; |
PS01281; GIDA_2; 1; |
From: TRMFO_BACSU (P39815) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND | 10 | 15 | FAD | G-x-G-[LIM]-[AS]-G |
Size range | 364-482 amino acids |
Related rules | MF_00129 (MNMG) |
Fusion | None |