HAMAP rule MF_01039
General rule information
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Accession | MF_01039 |
Dates | 12-DEC-2002 (Created) 1-JUN-2023 (Last updated, Version 41) |
Name | PGAM_GpmA |
Scope | Bacteria
Archaea |
Templates | P62707 (GPMA_ECOLI); Q3JWH7 (GPMA_BURP1); P9WIC9 (GPMA_MYCTU): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. |
Catalytic activity | RHEA:15901: (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate
EC 5.4.2.11 |
Pathway | Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. |
case <OC:Pseudomonadota>
Subunit | Homodimer. |
end case
Similarity | Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. |
Keywords
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Gene Ontology
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GO:0046538; Molecular function: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity.
GO:0006094; Biological process: gluconeogenesis.
GO:0006096; Biological process: glycolytic process.
GO:0006094; Biological process: gluconeogenesis.
GO:0006096; Biological process: glycolytic process.
Cross-references
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Features
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From: GPMA_ECOLI (P62707) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING (Optional) | 10 | 17 | /ligand="substrate | R-H-G-x-S-x(2)-[NK] | ||||||||
BINDING (Optional) | 23 | 24 | /ligand="substrate | [TS]-G | ||||||||
BINDING (Optional) | 89 | 92 | /ligand="substrate | E-[RK]-x-Y | ||||||||
BINDING (Optional) | 116 | 117 | /ligand="substrate | R-R | ||||||||
BINDING (Optional) | 185 | 186 | /ligand="substrate | G-N | ||||||||
ACT_SITE | 11 | 11 | Tele-phosphohistidine intermediate | H | ||||||||
ACT_SITE | 89 | 89 | Proton donor/acceptor | E | ||||||||
BINDING (Optional) | 62 | 62 | /ligand="substrate | R | ||||||||
BINDING (Optional) | 100 | 100 | /ligand="substrate | K | ||||||||
SITE | 184 | 184 | Transition state stabilizer | H |
Additional information
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Size range | 195-400 amino acids |
Related rules | MF_01040 (GPMB) |
Fusion | None |