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Annotation rule MF_01039 |
Accession | MF_01039 |
Dates | 12-DEC-2002 (Created) 19-NOV-2019 (Last updated, Version 36) |
Name | PGAM_GpmA |
Scope | Bacteria
Archaea |
Templates | P62707 (GPMA_ECOLI); Q3JWH7 (GPMA_BURP1); P9WIC9 (GPMA_MYCTU): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. |
Catalytic activity | RHEA:15901: (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate
EC 5.4.2.11 |
Pathway | Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. |
Subunit | Homodimer. |
Similarity | Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. |
From: GPMA_ECOLI (P62707) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION (Optional) | 10 | 17 | Substrate binding | R-H-G-x-S-x(2)-[NK] | ||||||||
REGION (Optional) | 23 | 24 | Substrate binding | [TS]-G | ||||||||
REGION (Optional) | 89 | 92 | Substrate binding | E-[RK]-x-Y | ||||||||
REGION (Optional) | 116 | 117 | Substrate binding | R-R | ||||||||
REGION (Optional) | 185 | 186 | Substrate binding | G-N | ||||||||
ACT_SITE | 11 | 11 | Tele-phosphohistidine intermediate | H | ||||||||
ACT_SITE | 89 | 89 | Proton donor/acceptor | E | ||||||||
BINDING (Optional) | 62 | 62 | Substrate | R | ||||||||
BINDING (Optional) | 100 | 100 | Substrate | K | ||||||||
SITE | 184 | 184 | Transition state stabilizer | H |
Size range | 195-400 amino acids |
Related rules | MF_01040 (GPMB) |
Fusion | None |