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Annotation rule MF_01050 |
Accession | MF_01050 |
Dates | 12-MAR-2003 (Created) 19-NOV-2019 (Last updated, Version 21) |
Name | CaiB |
Scope | Bacteria; Enterobacterales |
Templates | P31572 (CAIB_ECOLI); Q8GB19 (CAIB_PROSL): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. |
Catalytic activity | RHEA:28526: (R)-carnitine + crotonobetainyl-CoA = (R)-carnitinyl-CoA + crotonobetaine
EC 2.8.3.21 |
RHEA:28418: (R)-carnitine + gamma-butyrobetainyl-CoA = (R)-carnitinyl-CoA + 4-(trimethylamino)butanoate
EC 2.8.3.21 |
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Pathway | Amine and polyamine metabolism; carnitine metabolism. |
Subunit | Homodimer. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the CoA-transferase III family. CaiB subfamily. |
Pfam | PF02515; CoA_transf_3; 1; |
From: CAIB_ECOLI (P31572) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 169 | 169 | Nucleophile | D | ||||||||
BINDING | 97 | 97 | Coenzyme A | K | ||||||||
BINDING | 104 | 104 | Coenzyme A | R |
Size range | 405-406 amino acids |
Related rules | None |
Fusion | None |