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Annotation rule MF_01050
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General rule information [?]

Accession MF_01050
Dates 12-MAR-2003 (Created)
19-NOV-2019 (Last updated, Version 21)
Name CaiB
Scope
Bacteria; Enterobacterales
Templates P31572 (CAIB_ECOLI); Q8GB19 (CAIB_PROSL): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CAIB
Protein name
RecName: Full=L-carnitine CoA-transferase;
EC 2.8.3.21;
AltName: Full=Crotonobetainyl-CoA:carnitine CoA-transferase;
Gene name
caiB

Comments [?]

Function Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
Catalytic activity RHEA:28526: (R)-carnitine + crotonobetainyl-CoA = (R)-carnitinyl-CoA + crotonobetaine
EC 2.8.3.21
RHEA:28418: (R)-carnitine + gamma-butyrobetainyl-CoA = (R)-carnitinyl-CoA + 4-(trimethylamino)butanoate
EC 2.8.3.21
Pathway Amine and polyamine metabolism; carnitine metabolism.
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the CoA-transferase III family. CaiB subfamily.

Keywords [?]

Cytoplasm
Transferase

Gene Ontology [?]

GO:0008410; Molecular function: CoA-transferase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02515; CoA_transf_3; 1;

Features [?]

From: CAIB_ECOLI (P31572)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     169     169       Nucleophile     D  
BINDING     97     97       Coenzyme A     K  
BINDING     104     104       Coenzyme A     R  

Additional information [?]

Size range 405-406 amino acids
Related rules None
Fusion None


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