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Annotation rule MF_01052
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General rule information [?]

Accession MF_01052
Dates 26-MAR-2003 (Created)
19-NOV-2019 (Last updated, Version 19)
Name CaiA
Scope
Bacteria; Enterobacterales
Template P60584 (CAIA_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CAIA
Protein name
RecName: Full=Crotonobetainyl-CoA reductase;
EC 1.3.8.13;
AltName: Full=Crotonobetainyl-CoA dehydrogenase;
Gene name
caiA

Comments [?]

Function Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
Catalytic activity RHEA:51584: gamma-butyrobetainyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]
EC 1.3.8.13
Cofactor FAD
Pathway Amine and polyamine metabolism; carnitine metabolism.
Subunit Homotetramer.
Subcellular location Cytoplasm.
Similarity Belongs to the acyl-CoA dehydrogenase family.

Keywords [?]


Gene Ontology [?]

GO:0052890; Molecular function: oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor.
GO:0009437; Biological process: carnitine metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00441; Acyl-CoA_dh_1; 1;
PF02770; Acyl-CoA_dh_M; 1;
PF02771; Acyl-CoA_dh_N; 1;
PROSITE PS00072; ACYL_COA_DH_1; 1;
PS00073; ACYL_COA_DH_2; 1;

Additional information [?]

Size range 375-385 amino acids
Related rules None
Fusion None