HAMAP rule MF_01052

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01052
Accession	MF_01052
Dates	28-FEB-2005 (Created) 03-SEP-2024 (Last updated, Version 18)
Name	CaiA
Scope(s)	Bacteria Enterobacterales
Template(s)	P60584; [ Recover all ]
Triggered by	HAMAP; MF_01052 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CAIA
Protein name	RecName: Full=Crotonobetainyl-CoA reductase; EC=1.3.8.13; AltName: Full=Crotonobetainyl-CoA dehydrogenase;
Gene name	Name=caiA;

Comments [?]

FUNCTION	Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA.
CATALYTIC ACTIVITY	Reaction=4-(trimethylamino)butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = crotonobetainyl-CoA + reduced [electron- transfer flavoprotein]; Xref=Rhea:RHEA:51584, Rhea:RHEA-COMP:10685, Rhea:RHEA-COMP:10686, ChEBI:CHEBI:15378, ChEBI:CHEBI:57692, ChEBI:CHEBI:58307, ChEBI:CHEBI:60933, ChEBI:CHEBI:61513; EC=1.3.8.13;
COFACTOR	Name=FAD; Xref=ChEBI:CHEBI:57692;
PATHWAY	Amine and polyamine metabolism; carnitine metabolism.
SUBUNIT	Homotetramer.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the acyl-CoA dehydrogenase family.

Keywords [?]

Gene Ontology [?]

GO:0052890; Molecular function:oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

GO:0009437; Biological process:carnitine metabolic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]