 |
|
Annotation rule MF_01080 |
General rule information
[?]
Accession |
MF_01080 |
Dates |
24-SEP-2003 (Created) 19-NOV-2019 (Last updated, Version 25) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
|
Full=tRNA pseudouridine synthase B;
|
|
EC 5.4.99.25;
|
AltName:
|
Full=tRNA pseudouridine(55) synthase;
|
|
Short=Psi55 synthase;
|
AltName:
|
Full=tRNA pseudouridylate synthase;
|
AltName:
|
Full=tRNA-uridine isomerase;
|
|
Function |
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. |
Catalytic activity |
RHEA:42532: uridine(55) in tRNA = pseudouridine(55) in tRNA
EC 5.4.99.25
|
Similarity |
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. |
GO:0009982; Molecular function: pseudouridine synthase activity.
GO:0031119; Biological process: tRNA pseudouridine synthesis.
From: TRUB_ECOLI (P60340) |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
ACT_SITE
|
|
48
|
|
48
|
|
Nucleophile
|
|
|
|
D
|
|
|
case <OC:Enterobacterales>
BINDING
|
|
43
|
|
43
|
|
Substrate
|
|
|
|
H
|
|
|
BINDING
|
|
76
|
|
76
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
179
|
|
179
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
200
|
|
200
|
|
Substrate
|
|
|
|
L
|
|
|
end case
Additional information
[?]
Size range |
218-387 amino acids |
Related rules |
MF_01081 (TRUB) |
Fusion |
None |