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Annotation rule MF_01081 |
Accession | MF_01081 |
Dates | 25-SEP-2003 (Created) 19-NOV-2019 (Last updated, Version 23) |
Name | TruB_arch |
Scope | Archaea |
Templates | P60340 (TRUB_ECOLI); P9WHP7 (TRUB_MYCTU); Q9WZW0 (TRUB_THEMA): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. |
Catalytic activity | RHEA:42532: uridine(55) in tRNA = pseudouridine(55) in tRNA
EC 5.4.99.25 |
Similarity | Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. |
Pfam | PF01472; PUA; 1; |
PF01509; TruB_N; 1; | |
TIGRFAMs | TIGR00425; CBF5; 1; |
TIGR00451; Unchar_dom_2; 1; | |
TIGR00431; TruB; 1; | |
PROSITE | PS50890; PUA; 0-1; trigger=PRU00161; |
From: TRUB_ARCFU (O30001) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 69 | 69 | Nucleophile | D |
Size range | 301-365 amino acids |
Related rules | MF_01080 (TRUB) |
Fusion | None |
Comments | Active site is not conserved in AERPE. Shorter N-terminal in SACS2; not shown in alignment and not taken into account in size range. |