HAMAP rule MF_01100

General rule information [?]

Accession	MF_01100
Dates	16-JUL-2002 (Created) 19-NOV-2022 (Last updated, Version 31)

Name

5DNU

Scope

Bacteria; Gammaproteobacteria

Template

P76491 (5DNU_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

5DNU

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>

Protein name

RecName:		Full=5'-deoxynucleotidase YfbR;
		EC 3.1.3.89;
AltName:		Full=5'-deoxyribonucleotidase;
AltName:		Full=Nucleoside 5'-monophosphate phosphohydrolase;

Gene name

yfbR

end case

case not <OC:Escherichia> and not <OC:Shigella> and not <OC:Salmonella>

Protein name

RecName:		Full=5'-deoxynucleotidase ;
		EC 3.1.3.89;
AltName:		Full=5'-deoxyribonucleotidase;
AltName:		Full=Nucleoside 5'-monophosphate phosphohydrolase;

end case

Comments [?]

Function	Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
Catalytic activity	RHEA:36167: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate EC 3.1.3.89
Cofactor	a divalent metal cation
Subunit	Homodimer.
Subcellular location	Cytoplasm.
Similarity	Belongs to the 5DNU family.

Keywords [?]

Gene Ontology [?]

GO:0016791; Molecular function: phosphatase activity.

Cross-references [?]

Features [?]

From: 5DNU_ECOLI (P76491)

Key From To Description Tag Condition FTGroup

BINDING 18 19 /ligand="substrate R-W

BINDING 77 80 /ligand="substrate D-x-x-T

BINDING 33 33 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 H

BINDING 68 68 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 H

BINDING 69 69 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 D

BINDING 137 137 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 D

BINDING 33 33 /ligand="substrate H

BINDING 69 69 /ligand="substrate D

BINDING 137 137 /ligand="substrate D

SITE 18 18 Appears to be important in orienting the phosphate for catalysis R

Additional information [?]