HAMAP rule MF_01100
General rule information
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| Accession | MF_01100 |
| Dates | 16-JUL-2002 (Created)
19-NOV-2022 (Last updated, Version 31) |
| Name | 5DNU |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P76491 (5DNU_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01100 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | 5DNU |
| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| Protein name | RecName: Full=5'-deoxynucleotidase YfbR; EC=3.1.3.89; AltName: Full=5'-deoxyribonucleotidase; AltName: Full=Nucleoside 5'-monophosphate phosphohydrolase; |
| Gene name | Name=yfbR; |
| end case | |
| case not <OC:Escherichia> and not <OC:Shigella> and not <OC:Salmonella> | |
| Protein name | RecName: Full=5'-deoxynucleotidase EC=3.1.3.89; AltName: Full=5'-deoxyribonucleotidase; AltName: Full=Nucleoside 5'-monophosphate phosphohydrolase; |
| end case | |
Comments
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| FUNCTION | Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. |
| CATALYTIC ACTIVITY | Reaction=a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'- deoxyribonucleoside + phosphate; Xref=Rhea:RHEA:36167, ChEBI:CHEBI:15377, ChEBI:CHEBI:18274, ChEBI:CHEBI:43474, ChEBI:CHEBI:65317; EC=3.1.3.89; |
| COFACTOR | Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the 5DNU family. |
Keywords
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Gene Ontology
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| GO:0016791; Molecular function:phosphatase activity |
Cross-references
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Features
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| From: 5DNU_ECOLI (P76491) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 18 | 19 | /ligand="substrate" | R-W | ||||||||
| BINDING | 77 | 80 | /ligand="substrate" | D-x-x-T | ||||||||
| BINDING | 33 | 33 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
H | ||||||||
| BINDING | 68 | 68 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
H | ||||||||
| BINDING | 69 | 69 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
D | ||||||||
| BINDING | 137 | 137 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
D | ||||||||
| BINDING | 33 | 33 | /ligand="substrate" | H | ||||||||
| BINDING | 69 | 69 | /ligand="substrate" | D | ||||||||
| BINDING | 137 | 137 | /ligand="substrate" | D | ||||||||
| SITE | 18 | 18 | /note="Appears to be important in orienting the phosphate for catalysis" | R | ||||||||
Additional information
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| Size range | 194-199 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |