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Annotation rule MF_01108
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General rule information [?]

Accession MF_01108
Dates 27-MAR-2003 (Created)
2-MAR-2021 (Last updated, Version 35)
Name ArgE
Scope
Bacteria; Enterobacterales
Bacteria; Vibrionales
Template P23908 (ARGE_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARGE
Protein name
RecName: Full=Acetylornithine deacetylase;
Short=AO;
Short=Acetylornithinase;
EC 3.5.1.16;
AltName: Full=N-acetylornithinase;
Short=NAO;
Gene name
argE

Comments [?]

Catalytic activity RHEA:15941: H2O + N(2)-acetyl-L-ornithine = acetate + L-ornithine
EC 3.5.1.16
Cofactor Zn(2+)
Co(2+)
Note: Binds 2 Zn(2+) or Co(2+) ions per subunit.
glutathione
Pathway Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine from N(2)-acetyl-L-ornithine (linear): step 1/1.
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the peptidase M20A family. ArgE subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008777; Molecular function: acetylornithine deacetylase activity.
GO:0008270; Molecular function: zinc ion binding.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01546; Peptidase_M20; 1;
TIGRFAMs TIGR01892; AcOrn-deacetyl; 1;
PROSITE PS00758; ARGE_DAPE_CPG2_1; 1;
PS00759; ARGE_DAPE_CPG2_2; 1;

Features [?]

From: ARGE_ECOLI (P23908)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     82     82             D  
ACT_SITE     144     144             E  
METAL     80     80       Zinc 1     H  
METAL     112     112       Zinc 1     D  
METAL     112     112       Zinc 2     D  
METAL     145     145       Zinc 2     E  
METAL     169     169       Zinc 1     E  
METAL     355     355       Zinc 2     H  

Additional information [?]

Size range 378-389 amino acids
Related rules None
Fusion None