HAMAP rule MF_01110
General rule information
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Accession | MF_01110 |
Dates | 8-FEB-2003 (Created) 1-JUN-2023 (Last updated, Version 31) |
Name | ArgC_type2 |
Scope | Bacteria |
Template | P11446 (ARGC_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. |
Catalytic activity | RHEA:21588: N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH
EC 1.2.1.38 |
Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. |
Keywords
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Gene Ontology
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GO:0003942; Molecular function: N-acetyl-gamma-glutamyl-phosphate reductase activity.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Features
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From: ARGC_DEIRA (Q9RY72) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 117 | 117 | C |
Additional information
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Size range | 295-360 amino acids |
Related rules | None |
Fusion | None |
Comments | See MF_00150 for ArgC type 1 subfamily. |