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HAMAP rule MF_01110

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General rule information [?]

Accession MF_01110
Dates 8-FEB-2003 (Created)
1-JUN-2023 (Last updated, Version 31)
Name ArgC_type2
Scope(s) Bacteria
Template(s) P11446 (ARGC_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01110 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARGC
Protein name RecName: Full=N-acetyl-gamma-glutamyl-phosphate reductase;
                 Short=AGPR;
                 EC=1.2.1.38;
AltName: Full=N-acetyl-glutamate semialdehyde dehydrogenase;
                 Short=NAGSA dehydrogenase;
Gene name Name=argC;

Comments [?]

FUNCTIONCatalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
CATALYTIC ACTIVITY Reaction=N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH; Xref=Rhea:RHEA:21588, ChEBI:CHEBI:15378, ChEBI:CHEBI:29123, ChEBI:CHEBI:43474, ChEBI:CHEBI:57783, ChEBI:CHEBI:57936, ChEBI:CHEBI:58349; EC=1.2.1.38;
PATHWAYAmino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl- L-ornithine from L-glutamate: step 3/4.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the NAGSA dehydrogenase family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003942; Molecular function:N-acetyl-gamma-glutamyl-phosphate reductase activity
GO:0006526; Biological process:arginine biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01118; Semialdhyde_dh; 1;
PROSITE PS01224; ARGC; 1;
NCBIfam TIGR01851; argC_other; 1;

Features [?]

From: ARGC_DEIRA (Q9RY72)
Key From To Description Tag Condition FTGroup
ACT_SITE 117 117 C

Additional information [?]

Size range 295-360 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments See MF_00150 for ArgC type 1 subfamily.



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