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HAMAP rule MF_01116

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General rule information [?]

Accession MF_01116
Dates 27-NOV-2003 (Created)
19-NOV-2022 (Last updated, Version 26)
Name TSR3
Templates Q12094 (TSR3_YEAST); E1QU22 (TSR3_VULDI): [Recover all]
case <OC:Archaea>
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=16S rRNA aminocarboxypropyltransferase;
EC 2.5.1.-;

Comments [?]

Function Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
Catalytic activity RHEA:63296: an N(1)-methylpseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyl-N(3)[(3S)-3-amino-3-carboxypropyl]pseudouridine in 16S/18S rRNA + S-methyl-5'-thioadenosine
Subcellular location Cytoplasm.
Similarity Belongs to the TDD superfamily. TSR3 family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:1904047; Molecular function: S-adenosyl-L-methionine binding.
GO:0000455; Biological process: enzyme-directed rRNA pseudouridine synthesis.
GO:0006364; Biological process: rRNA processing.

Cross-references [?]

Pfam PF04034; Ribo_biogen_C; 1;
PF04068; RLI; 1;

Features [?]

From: TSR3_VULDI (E1QU22)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     19     19       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [TS]  
BINDING (Optional)     69     69       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [IVL]  
BINDING (Optional)     93     93       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [LI]  
BINDING (Optional)     108     108       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [YW]  
BINDING (Optional)     112     112       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [TS]  

Additional information [?]

Size range 163-208 amino acids
Related rules None
Fusion None