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Annotation rule MF_01117
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General rule information [?]

Accession MF_01117
Dates 20-NOV-2003 (Created)
19-NOV-2019 (Last updated, Version 28)
Name CDP_archaeol_synth
Scope
Archaea
Template O28534 (CDPAS_ARCFU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CDPAS
Protein name
RecName: Full=CDP-archaeol synthase;
EC 2.7.7.67;
AltName: Full=CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase;
Gene name
carS

Comments [?]

Function Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Catalytic activity RHEA:25690: 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H(+) = CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + diphosphate
EC 2.7.7.67
Cofactor Mg(2+)
Pathway Membrane lipid metabolism; glycerophospholipid metabolism.
Subcellular location Cell membrane; Multi-pass membrane protein.
Similarity Belongs to the CDP-archaeol synthase family.

Keywords [?]


Gene Ontology [?]

GO:0016779; Molecular function: nucleotidyltransferase activity.
GO:0046474; Biological process: glycerophospholipid biosynthetic process.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF01864; DUF46; 1;

Computed features [?]

General Transmembrane; -; 2-5; trigger=yes;

Additional information [?]

Size range 149-240 amino acids
Related rules None
Fusion None