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Annotation rule MF_01134
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General rule information [?]

Accession MF_01134
Dates 20-NOV-2003 (Created)
19-NOV-2019 (Last updated, Version 13)
Name CdhB
Scope
Archaea
Templates Q9C4Z3 (ACDE2_METTE); Q46G05 (ACDE1_METBF): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ACDE
Protein name
RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit epsilon;
Short=ACDS complex subunit epsilon;
AltName: Full=ACDS complex carbon monoxide dehydrogenase subunit epsilon;
Short=ACDS CODH subunit epsilon;
Gene name
cdhB

Comments [?]

case <OC:Methanosarcinaceae>
Function Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
end case
case not <OC:Methanosarcinaceae>
Function Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
end case
case <OC:Methanosarcinaceae>
Pathway One-carbon metabolism; methanogenesis from acetate.
end case
Subunit Heterotetramer of two alpha and two epsilon subunits. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta subunits with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
Similarity Belongs to the CdhB family.

Keywords [?]

case <OC:Methanosarcinaceae>
end case

Gene Ontology [?]

case <OC:Methanosarcinaceae>
GO:0019385; Biological process: methanogenesis, from acetate.
end case

Cross-references [?]

Pfam PF02552; CO_dh; 1;
TIGRFAMs TIGR00315; CdhB; 1;

Additional information [?]

Size range 146-187 amino acids
Related rules None
Fusion None