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Annotation rule MF_01136 |
General rule information
[?]
Accession |
MF_01136 |
Dates |
20-NOV-2003 (Created) 19-NOV-2019 (Last updated, Version 25) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Acetyl-CoA decarbonylase/synthase complex subunit gamma;
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Short=ACDS complex subunit gamma;
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EC 2.1.1.245;
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AltName:
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Full=5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase;
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AltName:
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Full=ACDS complex methyltransferase;
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AltName:
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Full=Corrinoid/iron-sulfur component large subunit;
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case <OC:Methanosarcinaceae>
Function |
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. |
end case
case not <OC:Methanosarcinaceae>
Function |
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). |
end case
Catalytic activity |
RHEA:45196: 5,6,7,8-tetrahydrosarcinapterin + [methyl-Co(III) corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + [Co(I) corrinoid Fe-S protein] + H(+)
EC 2.1.1.245
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Cofactor |
corrinoid |
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[4Fe-4S] cluster Note: Binds 1 [4Fe-4S] cluster. |
case <OC:Methanosarcinaceae>
Pathway |
One-carbon metabolism; methanogenesis from acetate. |
end case
Subunit |
Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8). |
case <OC:Methanosarcinaceae>
end case
case <FTGroup:1>
end case
case <FTGroup:1>
end case
GO:0008168; Molecular function: methyltransferase activity.
case <OC:Methanosarcinaceae>
GO:0019385; Biological process: methanogenesis, from acetate.
end case
From: ACDG1_METTE (Q50539) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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METAL
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18
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18
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Iron-sulfur (4Fe-4S)
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C
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1
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METAL
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21
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21
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Iron-sulfur (4Fe-4S)
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C
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1
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METAL
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26
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26
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Iron-sulfur (4Fe-4S)
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C
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1
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METAL
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43
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43
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Iron-sulfur (4Fe-4S)
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C
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1
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Additional information
[?]
Size range |
458-488 amino acids |
Related rules |
None |
Fusion |
None |