HAMAP rule MF_01136
General rule information
[?]
Accession | MF_01136 |
Dates | 20-NOV-2003 (Created) 19-NOV-2022 (Last updated, Version 28) |
Name | CdhE |
Scope | Archaea |
Template | Q50539 (ACDG1_METTE) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
case <OC:Methanosarcinaceae>
Function | Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. |
end case
case not <OC:Methanosarcinaceae>
Function | Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). |
end case
Catalytic activity | RHEA:45196: 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)
EC 2.1.1.245 |
Cofactor | corrinoid |
[4Fe-4S] cluster Note: Binds 1 [4Fe-4S] cluster. |
case <OC:Methanosarcinaceae>
Pathway | One-carbon metabolism; methanogenesis from acetate. |
end case
Subunit | Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8). |
Keywords
[?]
case <OC:Methanosarcinaceae>
end case
case <FTGroup:1>
end case
Gene Ontology
[?]
case <FTGroup:1>
GO:0005506; Molecular function: iron ion binding.
end case
GO:0008168; Molecular function: methyltransferase activity.
case <OC:Methanosarcinaceae>
GO:0019385; Biological process: methanogenesis, from acetate.
end case
Cross-references
[?]
Pfam | PF03599; CdhD; 1; |
PF04060; FeS; 1; | |
PROSITE | PS51656; 4FE4S; 1; trigger=PRU00989; |
PS00198; 4FE4S_FER_1; 1; |
Features
[?]
From: ACDG1_METTE (Q50539) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 18 | 18 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 21 | 21 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 26 | 26 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 43 | 43 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 |
Additional information
[?]
Size range | 458-488 amino acids |
Related rules | None |
Fusion | None |