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HAMAP rule MF_01140

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General rule information [?]

Accession MF_01140
Dates 2-MAR-2004 (Created)
1-JUN-2023 (Last updated, Version 33)
Name TagU_transferase
Scope(s) Bacteria
Template(s) Q02115 (TAGU_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01140 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TAGU
Protein name RecName: Full=Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU;
Gene name Name=tagU;

Comments [?]

FUNCTIONMay catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
PATHWAYCell wall biogenesis.
SUBCELLULAR LOCATIONCell membrane; Single-pass type II membrane protein.
SIMILARITYBelongs to the LytR/CpsA/Psr (LCP) family.

Keywords [?]

Gene Ontology [?]

GO:0016780; Molecular function:phosphotransferase activity, for other substituted phosphate groups
GO:0070726; Biological process:cell wall assembly
GO:0016020; Cellular component:membrane

Cross-references [?]

Pfam PF03816; LytR_cpsA_psr; 1;
NCBIfam TIGR00350; LytR_cpsA_psr; 1;

Features [?]

From: TAGU_BACSU (Q02115)
Key From To Description Tag Condition FTGroup
TOPO_DOM Nter 11 /note="Cytoplasmic"
TRANSMEM 12 32 /note="Helical; Signal-anchor for type II membrane protein"
TOPO_DOM 33 Cter /note="Extracellular"

Additional information [?]

Size range 300-340 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism.

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