HAMAP rule MF_01140

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01140
Accession	MF_01140
Dates	28-FEB-2005 (Created) 01-JUN-2023 (Last updated, Version 31)
Name	TagU_transferase
Scope(s)	Bacteria Bacillota
Template(s)	Q02115; [ Recover all ]
Triggered by	HAMAP; MF_01140 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TAGU
Protein name	RecName: Full=Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU; EC=2.7.8.-;
Gene name	Name=tagU;

Comments [?]

FUNCTION	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
PATHWAY	Cell wall biogenesis.
SUBCELLULAR LOCATION	Cell membrane; Single-pass type II membrane protein.
SIMILARITY	Belongs to the LytR/CpsA/Psr (LCP) family.

Keywords [?]

Gene Ontology [?]

GO:0016780; Molecular function:phosphotransferase activity, for other substituted phosphate groups

GO:0070726; Biological process:cell wall assembly

GO:0016020; Cellular component:membrane

Cross-references [?]

Pfam	PF03816; LytR_cpsA_psr; 1;
NCBIfam	TIGR00350; LytR_cpsA_psr; 1;

Features [?]

From: TAGU_BACSU (Q02115)

Key

From

Description

Tag

Condition

FTGroup

TOPO_DOM

Nter

/note="Cytoplasmic"

TRANSMEM

/note="Helical; Signal-anchor for type II membrane protein"

TOPO_DOM

Cter

/note="Extracellular"

Additional information [?]

Size range	300-340 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism.