HAMAP rule MF_01140
General rule information
[?]
Accession | MF_01140 |
Dates | 2-MAR-2004 (Created)
1-JUN-2023 (Last updated, Version 33) |
Name | TagU_transferase |
Scope(s) |
Bacteria Bacillota |
Template(s) | Q02115 (TAGU_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_01140 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | TAGU |
Protein name | RecName: Full=Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU; EC=2.7.8.-; |
Gene name | Name=tagU; |
Comments
[?]
FUNCTION | May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). |
PATHWAY | Cell wall biogenesis. |
SUBCELLULAR LOCATION | Cell membrane; Single-pass type II membrane protein. |
SIMILARITY | Belongs to the LytR/CpsA/Psr (LCP) family. |
Keywords
[?]
Cell membrane |
Cell wall biogenesis/degradation |
Membrane |
Signal-anchor |
Transferase |
Transmembrane |
Transmembrane helix |
Gene Ontology
[?]
GO:0016780; Molecular function:phosphotransferase activity, for other substituted phosphate groups |
GO:0070726; Biological process:cell wall assembly |
GO:0016020; Cellular component:membrane |
Cross-references
[?]
Features
[?]
From: TAGU_BACSU (Q02115) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 11 | /note="Cytoplasmic" | |||||||||
TRANSMEM | 12 | 32 | /note="Helical; Signal-anchor for type II membrane protein" | |||||||||
TOPO_DOM | 33 | Cter | /note="Extracellular" |
Additional information
[?]
Size range | 300-340 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism. |