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HAMAP rule MF_01140

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General rule information [?]

Accession MF_01140
Dates 2-MAR-2004 (Created)
13-JAN-2023 (Last updated, Version 32)
Name TagU_transferase
Scope
Bacteria; Bacillota
Template Q02115 (TAGU_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TAGU
Protein name
RecName: Full=Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU;
EC 2.7.8.-;
Gene name
tagU

Comments [?]

Function May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
Pathway Cell wall biogenesis.
Subcellular location Cell membrane; Single-pass type II membrane protein.
Similarity Belongs to the LytR/CpsA/Psr (LCP) family.

Keywords [?]


Gene Ontology [?]

GO:0016780; Molecular function: phosphotransferase activity, for other substituted phosphate groups.
GO:0070726; Biological process: cell wall assembly.
GO:0016020; Cellular component: membrane.

Cross-references [?]

Pfam PF03816; LytR_cpsA_psr; 1;
TIGRFAMs TIGR00350; LytR_cpsA_psr; 1;

Features [?]

From: TAGU_BACSU (Q02115)
Key     From     To       Description   Tag   Condition   FTGroup
TOPO_DOM     Nter     11       Cytoplasmic        
TRANSMEM     12     32       Helical; Signal-anchor for type II membrane protein        
TOPO_DOM     33     Cter       Extracellular        

Additional information [?]

Size range 300-340 amino acids
Related rules None
Fusion None
Comments The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism.