HAMAP rule MF_01140
General rule information
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| Accession | MF_01140 |
| Dates | 2-MAR-2004 (Created) 13-JAN-2023 (Last updated, Version 32) |
| Name | TagU_transferase |
| Scope | Bacteria; Bacillota |
| Template | Q02115 (TAGU_BACSU) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). |
| Pathway | Cell wall biogenesis. |
| Subcellular location | Cell membrane; Single-pass type II membrane protein. |
| Similarity | Belongs to the LytR/CpsA/Psr (LCP) family. |
Keywords
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Cell membrane
Cell wall biogenesis/degradation
Membrane
Signal-anchor
Transferase
Transmembrane
Transmembrane helix
Cell wall biogenesis/degradation
Membrane
Signal-anchor
Transferase
Transmembrane
Transmembrane helix
Gene Ontology
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GO:0016780; Molecular function: phosphotransferase activity, for other substituted phosphate groups.
GO:0070726; Biological process: cell wall assembly.
GO:0016020; Cellular component: membrane.
GO:0070726; Biological process: cell wall assembly.
GO:0016020; Cellular component: membrane.
Cross-references
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Features
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| From: TAGU_BACSU (Q02115) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 11 | Cytoplasmic | |||||||||
| TRANSMEM | 12 | 32 | Helical; Signal-anchor for type II membrane protein | |||||||||
| TOPO_DOM | 33 | Cter | Extracellular | |||||||||
Additional information
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| Size range | 300-340 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism. |