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Annotation rule MF_01145 |
General rule information
[?]
Accession |
MF_01145 |
Dates |
12-MAR-2004 (Created) 19-NOV-2019 (Last updated, Version 20) |
Scope |
Bacteria; Firmicutes |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Foldase protein PrsA;
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EC 5.2.1.8;
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Flags:
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Precursor;
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Function |
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. |
Catalytic activity |
RHEA:16237: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)
EC 5.2.1.8
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case <Feature:PS51257>
Subcellular location |
Cell membrane; Lipid-anchor. |
end case
Similarity |
Belongs to the PrsA family. |
case <Feature:PS51257>
end case
GO:0003755; Molecular function: peptidyl-prolyl cis-trans isomerase activity.
GO:0006457; Biological process: protein folding.
case <Feature:PS51257>
end case
Additional information
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Size range |
248-353 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
These proteins are typical of Gram-positive bacteria. They share low similarity and may be present in several copies per genome. Some do not possess the PPIase domain but are still active as foldases. |