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Annotation rule MF_01147 |
General rule information
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Accession |
MF_01147 |
Dates |
2-APR-2004 (Created) 19-NOV-2019 (Last updated, Version 32) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase;
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EC 2.5.1.145;
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Function |
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. |
Catalytic activity |
RHEA:56712: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate
EC 2.5.1.145
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Pathway |
Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the Lgt family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0008961; Molecular function: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity.
GO:0042158; Biological process: lipoprotein biosynthetic process.
GO:0005887; Cellular component: integral component of plasma membrane.
General |
Transmembrane; -; 5-9; trigger=yes; |
From: LGT_ECOLI (P60955) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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143
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143
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Lipid substrate
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R
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Additional information
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Size range |
243-492 amino acids |
Related rules |
None |
Fusion |
None |