HAMAP rule MF_01147
General rule information
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Accession | MF_01147 |
Dates | 2-APR-2004 (Created) 1-JUN-2023 (Last updated, Version 37) |
Name | Lgt |
Scope | Bacteria |
Templates | Q2G044 (LGT_STAA8); P60959 (LGT_SALTY): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. |
Catalytic activity | RHEA:56712: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate
EC 2.5.1.145 |
Pathway | Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the Lgt family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0008961; Molecular function: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity.
GO:0042158; Biological process: lipoprotein biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0042158; Biological process: lipoprotein biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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General | Transmembrane; -; 5-9; trigger=yes; |
Features
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From: LGT_ECOLI (P60955) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 143 | 143 | /ligand="1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)" /ligand_id="ChEBI:CHEBI:64716 | R |
Additional information
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Size range | 243-492 amino acids |
Related rules | None |
Fusion | None |