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Annotation rule MF_01164
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General rule information [?]

Accession MF_01164
Dates 27-MAY-2005 (Created)
19-NOV-2019 (Last updated, Version 34)
Name ArnC_transfer
Scope
Bacteria; Gammaproteobacteria
Template P77757 (ARNC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARNC
Protein name
RecName: Full=Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase;
EC 2.4.2.53;
AltName: Full=Undecaprenyl-phosphate Ara4FN transferase;
Short=Ara4FN transferase;
Gene name
arnC

Comments [?]

Function Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
Catalytic activity RHEA:27722: di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose = 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP
EC 2.4.2.53
Pathway Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 1/2.
Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the glycosyltransferase 2 family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0016780; Molecular function: phosphotransferase activity, for other substituted phosphate groups.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00535; Glycos_transf_2; 1;

Computed features [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
General Transmembrane; -; 2; trigger=yes;
ADD_TOPO_DOMAIN Cytoplasmic; -; 2; trigger=yes;
Periplasmic; -; 1; trigger=yes;
else
General Transmembrane; -; 2; trigger=yes;
end case

Additional information [?]

Size range 322-341 amino acids
Related rules None
Fusion None