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Annotation rule MF_01165 |
General rule information
[?]
Accession |
MF_01165 |
Dates |
16-JUN-2005 (Created) 19-NOV-2019 (Last updated, Version 30) |
Scope |
Bacteria; Gammaproteobacteria |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase;
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EC 2.4.2.43;
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AltName:
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Full=4-amino-4-deoxy-L-arabinose lipid A transferase;
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AltName:
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Full=Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase;
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AltName:
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Full=Undecaprenyl phosphate-alpha-L-Ara4N transferase;
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Function |
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
Catalytic activity |
Reaction=4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.; EC=2.4.2.43; |
Pathway |
Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the glycosyltransferase 83 family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0016740; Molecular function: transferase activity.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
General |
Transmembrane; -; 10-13; trigger=yes; |
Additional information
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Size range |
533-583 amino acids |
Related rules |
None |
Fusion |
None |