HAMAP rule MF_01165
General rule information
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Accession | MF_01165 |
Dates | 16-JUN-2005 (Created) 28-APR-2022 (Last updated, Version 31) |
Name | ArnT_transfer |
Scope | Bacteria; Gammaproteobacteria |
Templates | P76473 (ARNT_ECOLI); O52327 (ARNT_SALTY): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
Catalytic activity | Reaction=4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IVA = lipid IIA + di-trans,octa-cis-undecaprenyl phosphate.; EC=2.4.2.43; |
Pathway | Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the glycosyltransferase 83 family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Cell membrane
Glycosyltransferase
Lipid A biosynthesis
Lipid biosynthesis
Lipid metabolism
Lipopolysaccharide biosynthesis
Membrane
Transferase
Transmembrane
Transmembrane helix
Glycosyltransferase
Lipid A biosynthesis
Lipid biosynthesis
Lipid metabolism
Lipopolysaccharide biosynthesis
Membrane
Transferase
Transmembrane
Transmembrane helix
Gene Ontology
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GO:0016740; Molecular function: transferase activity.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF02366; PMT; 1; |
Computed features
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General | Transmembrane; -; 10-13; trigger=yes; |
Additional information
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Size range | 533-583 amino acids |
Related rules | None |
Fusion | None |