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HAMAP rule MF_01165

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General rule information [?]

Accession MF_01165
Dates 16-JUN-2005 (Created)
28-APR-2022 (Last updated, Version 31)
Name ArnT_transfer
Scope(s) Bacteria
Template(s) P76473 (ARNT_ECOLI); O52327 (ARNT_SALTY); [ Recover all ]
Triggered by HAMAP; MF_01165 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARNT
Protein name RecName: Full=Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase;
AltName: Full=4-amino-4-deoxy-L-arabinose lipid A transferase;
AltName: Full=Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase;
AltName: Full=Undecaprenyl phosphate-alpha-L-Ara4N transferase;
Gene name Name=arnT;

Comments [?]

FUNCTIONCatalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
CATALYTIC ACTIVITY Reaction=4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis- undecaprenyl phosphate + lipid IVA = lipid IIA + di-trans,octa-cis- undecaprenyl phosphate.; EC=;
PATHWAYLipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L- arabinose-lipid A biosynthesis.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the glycosyltransferase 83 family.

Keywords [?]

Gene Ontology [?]

GO:0016740; Molecular function:transferase activity
GO:0009245; Biological process:lipid A biosynthetic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF02366; PMT; 1;
General Transmembrane; -; 10-13;

Features [?]

Additional information [?]

Size range 533-583 amino acids
Related rules None
Fusion Nter: None Cter: None

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