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Annotation rule MF_01167
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General rule information [?]

Accession MF_01167
Dates 11-NOV-2005 (Created)
19-NOV-2019 (Last updated, Version 27)
Name ArnB_transfer
Scope
Bacteria; Gammaproteobacteria
Templates Q8ZNF3 (ARNB_SALTY); P77690 (ARNB_ECOLI): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARNB
Protein name
RecName: Full=UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase;
EC 2.6.1.87;
AltName: Full=UDP-4-amino-4-deoxy-L-arabinose aminotransferase;
AltName: Full=UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase;
Short=UDP-Ara4O aminotransferase;
Gene name
arnB

Comments [?]

Function Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
Catalytic activity RHEA:24710: 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose = L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose
EC 2.6.1.87
Cofactor pyridoxal 5'-phosphate
Pathway Nucleotide-sugar biosynthesis; UDP-4-deoxy-4-formamido-beta-L-arabinose biosynthesis; UDP-4-deoxy-4-formamido-beta-L-arabinose from UDP-alpha-D-glucuronate: step 2/3.
Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
Subunit Homodimer.
Similarity Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008483; Molecular function: transaminase activity.
GO:0046493; Biological process: lipid A metabolic process.

Cross-references [?]

Pfam PF01041; DegT_DnrJ_EryC1; 1;
PIRSF PIRSF000390; PLP_StrS; 1;

Features [?]

From: ARNB_SALTY (Q8ZNF3)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     188     188       N6-(pyridoxal phosphate)lysine     K  

Additional information [?]

Size range 378-388 amino acids
Related rules None
Fusion None