HAMAP rule MF_01176

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01176
Accession	MF_01176
Dates	23-NOV-2006 (Created) 01-JUN-2023 (Last updated, Version 25)
Name	HTH_type_IscR
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P0AGK8; [ Recover all ]
Triggered by	HAMAP; MF_01176 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ISCR
Protein name	RecName: Full=HTH-type transcriptional regulator IscR;
Gene name	Name=iscR;

Comments [?]

FUNCTION	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
case <FTGroup:1>
COFACTOR	Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Note=Binds 1 [2Fe-2S] cluster.;
end case

Keywords [?]

Gene Ontology [?]

GO:0003690; Molecular function:double-stranded DNA binding
case <FTGroup:1>
GO:0005506; Molecular function:iron ion binding
end case
GO:0003700; Molecular function:DNA-binding transcription factor activity
GO:0006355; Biological process:regulation of DNA-templated transcription

Cross-references [?]

Features [?]

From: ISCR_ECOLI (P0AGK8)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="[2Fe-2S] cluster"
/ligand_id="ChEBI:CHEBI:190135"

BINDING

/ligand="[2Fe-2S] cluster"
/ligand_id="ChEBI:CHEBI:190135"

BINDING

104

/ligand="[2Fe-2S] cluster"
/ligand_id="ChEBI:CHEBI:190135"

Additional information [?]