HAMAP logo

HAMAP rule MF_01176

Send feedback

General rule information [?]

Accession MF_01176
Dates 23-NOV-2006 (Created)
1-JUN-2023 (Last updated, Version 24)
Name HTH_type_IscR
Scope(s) Bacteria
Template(s) P0AGK8 (ISCR_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01176 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ISCR
Protein name RecName: Full=HTH-type transcriptional regulator IscR;
Gene name Name=iscR;

Comments [?]

FUNCTIONRegulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
case <FTGroup:1>
COFACTOR Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Note=Binds 1 [2Fe-2S] cluster.;
end case

Keywords [?]

Gene Ontology [?]

GO:0003690; Molecular function:double-stranded DNA binding
case <FTGroup:1>
GO:0005506; Molecular function:iron ion binding
end case
GO:0003700; Molecular function:DNA-binding transcription factor activity
GO:0006355; Biological process:regulation of DNA-templated transcription

Cross-references [?]

PROSITE PS01332; HTH_RRF2_1; 1;
PROSITE PS51197; HTH_RRF2_2; 1;
Pfam PF02082; Rrf2; 1;
NCBIfam TIGR02010; IscR; 1;
NCBIfam TIGR00738; Rrf2_super; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 92 92 /ligand="[2Fe-2S] cluster"
C 1
BINDING 98 98 /ligand="[2Fe-2S] cluster"
C 1
BINDING 104 104 /ligand="[2Fe-2S] cluster"
C 1

Additional information [?]

Size range 162-173 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)