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Annotation rule MF_01176
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General rule information [?]

Accession MF_01176
Dates 23-NOV-2006 (Created)
19-NOV-2019 (Last updated, Version 19)
Name HTH_type_IscR
Scope
Bacteria; Gammaproteobacteria
Template P0AGK8 (ISCR_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ISCR
Protein name
RecName: Full=HTH-type transcriptional regulator IscR;
Gene name
iscR

Comments [?]

Function Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
case <FTGroup:1>
Cofactor [2Fe-2S] cluster
Note: Binds 1 [2Fe-2S] cluster.
end case

Keywords [?]

case <FTGroup:1>
2Fe-2S
end case
Activator
DNA-binding
case <FTGroup:1>
Iron
Iron-sulfur
Metal-binding
end case
Repressor
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003690; Molecular function: double-stranded DNA binding.
case <FTGroup:1>
GO:0005506; Molecular function: iron ion binding.
end case
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0006355; Biological process: regulation of transcription, DNA-templated.

Cross-references [?]

PROSITE PS01332; HTH_RRF2_1; 1;
PS51197; HTH_RRF2_2; 1; trigger=PRU00540;
Pfam PF02082; Rrf2; 1;
TIGRFAMs TIGR02010; IscR; 1;
TIGR00738; Rrf2_super; 1;

Features [?]

From: ISCR_ECOLI (P0AGK8)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     92     92       Iron-sulfur (2Fe-2S)     C   1
METAL     98     98       Iron-sulfur (2Fe-2S)     C   1
METAL     104     104       Iron-sulfur (2Fe-2S)     C   1

Additional information [?]

Size range 162-173 amino acids
Related rules None
Fusion None


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