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Annotation rule MF_01184 |
Accession | MF_01184 |
Dates | 6-MAY-2008 (Created) 19-NOV-2019 (Last updated, Version 15) |
Name | XPRTase |
Scope | Bacteria |
Template | P42085 (XPT_BACSU) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. |
Catalytic activity | RHEA:10800: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine
EC 2.4.2.22 |
Pathway | Purine metabolism; XMP biosynthesis via salvage pathway; XMP from xanthine: step 1/1. |
Subunit | Homodimer. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily. |
PROSITE | PS00103; PUR_PYR_PR_TRANSFER; 1; |
Pfam | PF00156; Pribosyltran; 1; |
TIGRFAMs | TIGR01744; XPRTase; 1; |
From: XPT_BACSU (P42085) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 128 | 132 | 5-phospho-alpha-D-ribose 1-diphosphate binding | |||||||||
BINDING | 20 | 20 | Xanthine; via amide nitrogen and carbonyl oxygen | L | ||||||||
BINDING | 27 | 27 | Xanthine | [NT] | ||||||||
BINDING | 156 | 156 | Xanthine | K |
Size range | 188-211 amino acids |
Related rules | None |
Fusion | None |