HAMAP rule MF_01190
General rule information
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| Accession | MF_01190 |
| Dates | 15-JUN-2007 (Created)
28-JUN-2022 (Last updated, Version 21) |
| Name | HTH_type_FabR |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P0ACU5 (FABR_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01190 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | FABR |
| Protein name | RecName: Full=HTH-type transcriptional repressor FabR; |
| Gene name | Name=fabR; |
Comments
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| FUNCTION | Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
Keywords
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| Cytoplasm |
| DNA-binding |
| Fatty acid biosynthesis |
| Fatty acid metabolism |
| Lipid biosynthesis |
| Lipid metabolism |
| Repressor |
| Transcription |
| Transcription regulation |
Gene Ontology
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| GO:0003700; Molecular function:DNA-binding transcription factor activity |
| GO:0006633; Biological process:fatty acid biosynthetic process |
| GO:0045717; Biological process:negative regulation of fatty acid biosynthetic process |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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| Size range | 200-250 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |