HAMAP rule MF_01190

General rule information [?]

Accession	MF_01190
Dates	15-JUN-2007 (Created) 28-JUN-2022 (Last updated, Version 21)

Name	HTH_type_FabR

Scope

Bacteria; Enterobacterales

Template

P0ACU5 (FABR_ECOLI)

Triggered by

HAMAP; MF_01190 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

FABR

Protein name

RecName:

Full=HTH-type transcriptional repressor FabR;

Gene name

fabR

Comments [?]

Function	Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
Subunit	Homodimer.
Subcellular location	Cytoplasm.

Keywords [?]

Cytoplasm
DNA-binding
Fatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
Repressor
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0045717; Biological process: negative regulation of fatty acid biosynthetic process.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS01081; HTH_TETR_1; 1;
	PS50977; HTH_TETR_2; 1; trigger=PRU00335;
Pfam	PF00440; TetR_N; 1;

Additional information [?]

Size range	200-250 amino acids
Related rules	None
Fusion	None

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