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HAMAP rule MF_01190

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General rule information [?]

Accession MF_01190
Dates 15-JUN-2007 (Created)
28-JUN-2022 (Last updated, Version 21)
Name HTH_type_FabR
Scope
Bacteria; Enterobacterales
Template P0ACU5 (FABR_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FABR
Protein name
RecName: Full=HTH-type transcriptional repressor FabR;
Gene name
fabR

Comments [?]

Function Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
Subunit Homodimer.
Subcellular location Cytoplasm.

Keywords [?]


Gene Ontology [?]

GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0045717; Biological process: negative regulation of fatty acid biosynthetic process.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS01081; HTH_TETR_1; 1;
PS50977; HTH_TETR_2; 1; trigger=PRU00335;
Pfam PF00440; TetR_N; 1;

Additional information [?]

Size range 200-250 amino acids
Related rules None
Fusion None