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Annotation rule MF_01198 |
Accession | MF_01198 |
Dates | 2-MAY-2008 (Created) 19-NOV-2019 (Last updated, Version 10) |
Name | Anti_adapt_IraP |
Scope | Bacteria; Enterobacteriaceae |
Template | P0AAN9 (IRAP_ECOLI) |
Triggered by |
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Protein name |
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Function | Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. |
Function | Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. |
Subunit | Interacts with RssB. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the IraP family. |
Pfam | PF10796; Anti-adapt_IraP; 1; |
General | Coiled_coil; -; 1-unlimited; trigger=yes; |
Size range | 86-86 amino acids |
Related rules | None |
Fusion | None |