HAMAP rule MF_01198

General rule information [?]

Accession	MF_01198
Dates	2-MAY-2008 (Created) 19-NOV-2019 (Last updated, Version 10)
Name	Anti_adapt_IraP
Scope(s)	Bacteria Enterobacteriaceae
Template(s)	P0AAN9 (IRAP_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01198 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	IRAP
Protein name	RecName: Full=Anti-adapter protein IraP;
Gene name	Name=iraP;

Comments [?]

case <OC:Salmonella>
FUNCTION	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
else
FUNCTION	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
end case
SUBUNIT	Interacts with RssB.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the IraP family.

Keywords [?]

Gene Ontology [?]

GO:0009267; Biological process:cellular response to starvation

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF10796; Anti-adapt_IraP; 1;
General	Coiled_coil; -; 1-unlimited;

Features [?]

Additional information [?]