HAMAP rule MF_01203
General rule information
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Accession | MF_01203 |
Dates | 8-FEB-2002 (Created) 19-NOV-2019 (Last updated, Version 34) |
Name | CLC_ClcB |
Scope | Bacteria |
Template | P76175 (CLCB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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case <OC:Enterobacterales>
Identifier |
|
Protein name |
|
Gene name |
|
else
Identifier |
|
Protein name |
|
end case
Comments
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case <OC:Enterobacterales>
Function | Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. |
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0005247; Molecular function: voltage-gated chloride channel activity.
GO:0006821; Biological process: chloride transport.
GO:0005886; Cellular component: plasma membrane.
GO:0006821; Biological process: chloride transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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General | Transmembrane; -; 9-11; trigger=yes; |
Additional information
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Size range | 414-461 amino acids |
Related rules | None |
Fusion | None |
Comments | In view of recent findings for ClcA in E.coli, ClcB may also be an exchange transporter and not a voltage-gated channel. |