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Annotation rule MF_01203 |
General rule information
[?]
Accession |
MF_01203 |
Dates |
8-FEB-2002 (Created) 19-NOV-2019 (Last updated, Version 34) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Enterobacterales>
Protein name |
RecName:
|
Full=Voltage-gated ClC-type chloride channel ClcB;
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|
else
Protein name |
RecName:
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Full=Putative chloride channel protein ClcB-like;
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|
end case
case <OC:Enterobacterales>
Function |
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. |
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0005247; Molecular function: voltage-gated chloride channel activity.
GO:0006821; Biological process: chloride transport.
GO:0005886; Cellular component: plasma membrane.
General |
Transmembrane; -; 9-11; trigger=yes; |
Additional information
[?]
Size range |
414-461 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
In view of recent findings for ClcA in E.coli, ClcB may also be an exchange transporter and not a voltage-gated channel. |