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Annotation rule MF_01215
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General rule information [?]

Accession MF_01215
Dates 10-JUN-2002 (Created)
19-NOV-2019 (Last updated, Version 25)
Name OMPdecase_type2
Scope
Bacteria
Archaea
Templates P0A5M7 (PYRF_MYCBO); P96076 (PYRF_THET2): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PYRF
Protein name
RecName: Full=Orotidine 5'-phosphate decarboxylase;
EC 4.1.1.23;
AltName: Full=OMP decarboxylase;
Short=OMPDCase;
Short=OMPdecase;
Gene name
pyrF

Comments [?]

Catalytic activity RHEA:11596: H(+) + orotidine 5'-phosphate = CO2 + UMP
EC 4.1.1.23
Pathway Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
Similarity Belongs to the OMP decarboxylase family. Type 2 subfamily.

Keywords [?]

Lyase
Decarboxylase
Pyrimidine biosynthesis

Gene Ontology [?]

GO:0004590; Molecular function: orotidine-5'-phosphate decarboxylase activity.
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process.

Cross-references [?]

Pfam PF00215; OMPdecase; 1;
PROSITE PS00156; OMPDECASE; 1;
TIGRFAMs TIGR02127; pyrF_sub2; 1;

Features [?]

From: PYRF_DEIRA (Q9RSC5)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     92     92       Proton donor     K  

Additional information [?]

Size range 267-307 amino acids
Related rules MF_01200 (PYRF)
Fusion Nter: None; Cter: MF_01208 (pyrE)
Comments Divergent NOSS1; sequence not included in alignment


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