HAMAP rule MF_01238

General rule information [?]

Accession	MF_01238
Dates	29-APR-2003 (Created) 1-JUN-2023 (Last updated, Version 30)

Name

MFS_NanT

Scope

Bacteria; Enterobacterales

Template

P41036 (NANT_ECOLI)

Triggered by

HAMAP; MF_01238 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

NANT

Protein name

RecName:		Full=Sialic acid transporter NanT;
AltName:		Full=Sialic acid permease;
AltName:		Full=Sialic acid/H(+) symporter;

Gene name

nanT

Comments [?]

Function	Catalyzes the proton-dependent transport of sialic acid.
Catalytic activity	RHEA:28987: H(+)(in) + N-acetylneuraminate(in) = H(+)(out) + N-acetylneuraminate(out)
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Similarity	Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.

Keywords [?]

Transport
Sugar transport
Transmembrane
Membrane
Cell membrane
Cell inner membrane
Transmembrane helix

Gene Ontology [?]

GO:0015538; Molecular function: sialic acid:proton symporter activity.
GO:0015739; Biological process: sialic acid transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam	PF07690; MFS_1; 1;
NCBIfam	TIGR00891; 2A0112; 1;
PROSITE	PS50850; MFS; 1;
	PS00216; SUGAR_TRANSPORT_1; 1;
	PS00217; SUGAR_TRANSPORT_2; 1;

Computed features [?]

General

Transmembrane; -; 12-14; trigger=yes;

Additional information [?]

Size range	480-515 amino acids
Related rules	None
Fusion	None
Comments	Possible wrong start in the second copy in ECOL6

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