HAMAP rule MF_01238
General rule information
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Accession | MF_01238 |
Dates | 29-APR-2003 (Created)
1-JUN-2023 (Last updated, Version 30) |
Name | MFS_NanT |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P41036 (NANT_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01238 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NANT |
Protein name | RecName: Full=Sialic acid transporter NanT; AltName: Full=Sialic acid permease; AltName: Full=Sialic acid/H(+) symporter; |
Gene name | Name=nanT; |
Comments
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FUNCTION | Catalyzes the proton-dependent transport of sialic acid. |
CATALYTIC ACTIVITY | Reaction=H(+)(in) + N-acetylneuraminate(in) = H(+)(out) + N- acetylneuraminate(out); Xref=Rhea:RHEA:28987, ChEBI:CHEBI:15378, ChEBI:CHEBI:35418; |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
SIMILARITY | Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. |
Keywords
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Transport |
Sugar transport |
Transmembrane |
Membrane |
Cell membrane |
Cell inner membrane |
Transmembrane helix |
Gene Ontology
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GO:0015538; Molecular function:sialic acid:proton symporter activity |
GO:0015739; Biological process:sialic acid transport |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF07690; MFS_1; 1; |
NCBIfam | TIGR00891; 2A0112; 1; |
PROSITE | PS50850; MFS; 1; |
PROSITE | PS00216; SUGAR_TRANSPORT_1; 1; |
PROSITE | PS00217; SUGAR_TRANSPORT_2; 1; |
General | Transmembrane; -; 12-14; |
Features
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Additional information
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Size range | 480-515 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | Possible wrong start in the second copy in ECOL6 |