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Annotation rule MF_01247
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General rule information [?]

Accession MF_01247
Dates 6-APR-2004 (Created)
19-NOV-2019 (Last updated, Version 22)
Name HTH_type_MalT
Scope
Bacteria; Gammaproteobacteria
Template P06993 (MALT_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MALT
Protein name
RecName: Full=HTH-type transcriptional regulator MalT;
AltName: Full=ATP-dependent transcriptional activator MalT;
Gene name
malT

Comments [?]

Function Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
Activity regulation Activated by ATP and maltotriose, which are both required for DNA binding.
Subunit Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
Similarity Belongs to the MalT family.

Keywords [?]

DNA-binding
Transcription
Transcription regulation
Activator
ATP-binding
Nucleotide-binding
Carbohydrate metabolism

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0045913; Biological process: positive regulation of carbohydrate metabolic process.
GO:0045893; Biological process: positive regulation of transcription, DNA-templated.

Cross-references [?]

Pfam PF00196; GerE; 1;
PRINTS PR00038; HTHLUXR; 1;
PROSITE PS00622; HTH_LUXR_1; 1;
PS50043; HTH_LUXR_2; 1; trigger=PRU00411;

Features [?]

From: MALT_ECOLI (P06993)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     39     46       ATP     x-P-[AS]-G-[YF]-G-K-[TS]  

Additional information [?]

Size range 870-940 amino acids
Related rules None
Fusion None


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