HAMAP rule MF_01247

General rule information [?]

Accession	MF_01247
Dates	6-APR-2004 (Created) 19-NOV-2022 (Last updated, Version 25)

Name	HTH_type_MalT

Scope

Bacteria; Gammaproteobacteria

Template

P06993 (MALT_ECOLI)

Triggered by

HAMAP; MF_01247 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MALT

Protein name

RecName:		Full=HTH-type transcriptional regulator MalT;
AltName:		Full=ATP-dependent transcriptional activator MalT;

Gene name

malT

Comments [?]

Function	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
Activity regulation	Activated by ATP and maltotriose, which are both required for DNA binding.
Subunit	Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
Similarity	Belongs to the MalT family.

Keywords [?]

DNA-binding
Transcription
Transcription regulation
Activator
ATP-binding
Nucleotide-binding
Carbohydrate metabolism

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0045913; Biological process: positive regulation of carbohydrate metabolic process.
GO:0045893; Biological process: positive regulation of DNA-templated transcription.

Cross-references [?]

Pfam	PF00196; GerE; 1;
PRINTS	PR00038; HTHLUXR; 1;
PROSITE	PS00622; HTH_LUXR_1; 1;
	PS50043; HTH_LUXR_2; 1; trigger=PRU00411;

Features [?]

From: MALT_ECOLI (P06993)

Key From To Description Tag Condition FTGroup

BINDING 39 46 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 x-P-[AS]-G-[YF]-G-K-[TS]

Additional information [?]

Size range	870-940 amino acids
Related rules	None
Fusion	None

View rule in raw text format (no links)