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HAMAP rule MF_01247

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General rule information [?]

Accession MF_01247
Dates 6-APR-2004 (Created)
19-NOV-2022 (Last updated, Version 25)
Name HTH_type_MalT
Scope(s) Bacteria
Gammaproteobacteria
Template(s) P06993 (MALT_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01247 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MALT
Protein name RecName: Full=HTH-type transcriptional regulator MalT;
AltName: Full=ATP-dependent transcriptional activator MalT;
Gene name Name=malT;

Comments [?]

FUNCTIONPositively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
ACTIVITY REGULATIONActivated by ATP and maltotriose, which are both required for DNA binding.
SUBUNITMonomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
SIMILARITYBelongs to the MalT family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003700; Molecular function:DNA-binding transcription factor activity
GO:0045913; Biological process:positive regulation of carbohydrate metabolic process
GO:0045893; Biological process:positive regulation of DNA-templated transcription

Cross-references [?]

Pfam PF00196; GerE; 1;
PRINTS PR00038; HTHLUXR; 1;
PROSITE PS00622; HTH_LUXR_1; 1;
PROSITE PS50043; HTH_LUXR_2; 1;

Features [?]

From: MALT_ECOLI (P06993)
Key From To Description Tag Condition FTGroup
BINDING 39 46 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
x-P-[AS]-G-[YF]-G-K-[TS]

Additional information [?]

Size range 870-940 amino acids
Related rules None
Fusion Nter: None Cter: None



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