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Annotation rule MF_01250
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General rule information [?]

Accession MF_01250
Dates 3-AUG-2004 (Created)
19-NOV-2019 (Last updated, Version 13)
Name Pyrophosphat_PpaX
Scope
Bacteria; Bacillales
Bacteria; Clostridia
Template Q9JMQ2 (PPAX_BACSU)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PPAX
case <OC:Bacillales>
Protein name
RecName: Full=Pyrophosphatase PpaX;
EC 3.6.1.1;
end case
case not <OC:Bacillales>
Protein name
RecName: Full=Putative pyrophosphatase PpaX;
EC 3.6.1.1;
end case
Gene name
ppaX

Comments [?]

case <OC:Bacillales>
Function Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.
end case
Catalytic activity RHEA:24576: diphosphate + H2O = H(+) + 2 phosphate
EC 3.6.1.1
Cofactor Mg(2+)
Similarity Belongs to the HAD-like hydrolase superfamily. PpaX family.

Keywords [?]

Hydrolase
Magnesium

Gene Ontology [?]

GO:0000287; Molecular function: magnesium ion binding.
GO:0004427; Molecular function: inorganic diphosphatase activity.

Cross-references [?]

Pfam PF00702; Hydrolase; 1;
PRINTS PR00413; HADHALOGNASE; 1;
TIGRFAMs TIGR01549; HAD-SF-IA-v1; 1;
TIGR01509; HAD-SF-IA-v3; 1;
TIGR02009; PGMB-YQAB-SF; 1;

Features [?]

From: PPAX_BACSU (Q9JMQ2)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     12     12       Nucleophile     D  

Additional information [?]

Size range 214-220 amino acids
Related rules None
Fusion None
Comments In Bacillales, the gene corresponding to this protein is located in the proximity of hprK gene which encodes HPr kinase/phosphorylase.


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