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Annotation rule MF_01271 |
General rule information
[?]
Accession |
MF_01271 |
Dates |
8-NOV-2006 (Created) 14-MAY-2022 (Last updated, Version 14) |
Scope |
Bacteria; Gammaproteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=N-acetyl-D-glucosamine kinase;
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EC 2.7.1.59;
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AltName:
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Full=GlcNAc kinase;
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Function |
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. |
Catalytic activity |
RHEA:17417: ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate
EC 2.7.1.59
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Pathway |
Cell wall biogenesis; peptidoglycan recycling. |
Similarity |
Belongs to the ROK (NagC/XylR) family. NagK subfamily. |
case <FTGroup:1>
end case
case <FTGroup:1>
end case
GO:0045127; Molecular function: N-acetylglucosamine kinase activity.
GO:0006044; Biological process: N-acetylglucosamine metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.
From: NAGK_ECOLI (P75959) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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4
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11
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/ligand="ATP" /ligand_id="30616
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BINDING
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133
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140
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/ligand="ATP" /ligand_id="30616
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BINDING (Optional)
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157
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157
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/ligand="Zn(2+)" /ligand_id="29105
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H
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1
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BINDING (Optional)
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177
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177
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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BINDING (Optional)
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179
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179
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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BINDING (Optional)
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184
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184
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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Additional information
[?]
Size range |
256-305 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
NagK sequences from YERPE, YERPA and YERPN (but not YERPS) are shorter, due to a probable natural frameshift in the C-terminus; they are not included in alignment. |