HAMAP rule MF_01273

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01273
Accession	MF_01273
Dates	08-NOV-2006 (Created) 01-JUN-2023 (Last updated, Version 19)
Name	Pantothen_kinase_2
Scope(s)	Bacteria Bacillota
Template(s)	Q2FWC7; Q6G7I0; [ Recover all ]
Triggered by	HAMAP; MF_01273 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	COAW
Protein name	RecName: Full=Type II pantothenate kinase; EC=2.7.1.33; AltName: Full=PanK-II; AltName: Full=Pantothenic acid kinase;
Gene name	Name=coaW;

Comments [?]

FUNCTION	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
CATALYTIC ACTIVITY	Reaction=(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+); Xref=Rhea:RHEA:16373, ChEBI:CHEBI:10986, ChEBI:CHEBI:15378, ChEBI:CHEBI:29032, ChEBI:CHEBI:30616, ChEBI:CHEBI:456216; EC=2.7.1.33;
PATHWAY	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)- pantothenate: step 1/5.
SUBUNIT	Homodimer.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the type II pantothenate kinase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0004594; Molecular function:pantothenate kinase activity

GO:0015937; Biological process:coenzyme A biosynthetic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF03630; Fumble; 1;
NCBIfam	TIGR00555; PanK_eukar; 1;

Features [?]

From: COAW_STAAS (Q6G7I0)

Key

From

Description

Tag

Condition

FTGroup

BINDING