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Annotation rule MF_01289 |
General rule information
[?]
Accession |
MF_01289 |
Dates |
19-SEP-2008 (Created) 19-NOV-2019 (Last updated, Version 14) |
Scope |
Bacteria; Proteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=D-galactonate dehydratase;
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Short=GalD;
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EC 4.2.1.6;
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Function |
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate. |
Catalytic activity |
RHEA:18649: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O
EC 4.2.1.6
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case <FTGroup:1>
Cofactor |
Mg(2+) Note: Binds 1 Mg(2+) ion per subunit. |
end case
Pathway |
Carbohydrate acid metabolism; D-galactonate degradation; D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 1/3. |
Miscellaneous |
Reaction proceeds via an anti dehydration. |
Similarity |
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily. |
case <FTGroup:1>
end case
case <FTGroup:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
GO:0008869; Molecular function: galactonate dehydratase activity.
GO:0034194; Biological process: D-galactonate catabolic process.
From: DGOD_ECOLI (Q6BF17) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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185
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185
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Proton donor/acceptor
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H
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ACT_SITE
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285
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285
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Proton donor/acceptor
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H
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METAL
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183
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183
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Magnesium
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D
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1
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METAL
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209
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209
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Magnesium
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|
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E
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1
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METAL
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235
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235
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Magnesium
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E
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1
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SITE
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258
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258
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Increases basicity of active site His
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D
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SITE
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310
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310
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Transition state stabilizer
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E
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Additional information
[?]
Size range |
365-385 amino acids |
Related rules |
None |
Fusion |
None |