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HAMAP rule MF_01306

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General rule information [?]

Accession MF_01306
Dates 3-DEC-2002 (Created)
17-FEB-2023 (Last updated, Version 33)
Name Ribosomal_S4
Scope
Bacteria
Archaea
Plastid
Templates P81288 (RS4_GEOSE); P21466 (RS4_BACSU); P0A7V8 (RS4_ECOLI); O54297 (RS4_SALTY); P80373 (RS4_THET8); P48270 (RR4_CHLRE): [Recover all]
case <OC:Bacteria> or <OG:Chloroplast>
Triggered by
end case

case <OC:Archaea>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
Identifier
RS4
Protein name
RecName: Full=30S ribosomal protein S4;
Gene name
rpsD
else case <OC:Cyanobacteriota>
Identifier
RS4
Protein name
RecName: Full=30S ribosomal protein S4;
Gene name
rpsD, rps4
else case <OC:Archaea>
Identifier
RS4
Protein name
RecName: Full=30S ribosomal protein S4;
Gene name
rps4
else case <OG:Chloroplast>
Identifier
RR4
Protein name
RecName: Full=30S ribosomal protein S4, chloroplastic;
Gene name
rps4
end case

Comments [?]

Function One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
With S5 and S12 plays an important role in translational accuracy.
Subunit Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the universal ribosomal protein uS4 family.

Keywords [?]

Ribonucleoprotein
Ribosomal protein
RNA-binding
rRNA-binding

Gene Ontology [?]

GO:0019843; Molecular function: rRNA binding.
GO:0006412; Biological process: translation.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF00163; Ribosomal_S4; 1;
PF01479; S4; 1;
TIGRFAMs TIGR01018; RpsD_arch; 1;
TIGR01017; RpsD_bact; 1;
PROSITE PS00632; RIBOSOMAL_S4; 1;
PS50889; S4; 1; trigger=PRU00182;

Additional information [?]

case <OC:Bacteria>
Size range 192-257 amino acids
end case
case <OC:Archaea>
Size range 159-219 amino acids
end case
Related rules None
Fusion None
Comments Some plastid-encoded rps4 sequences (EIMTE, HELSJ, STIHE, TOXGO), as well as CARRP and NEOSM are quite divergent and thus have been made atypical. The second and third copies in the Clostridia have also been made atypical. In AZOSB the second copy is truncated and probably not functional.


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