HAMAP rule MF_01333
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01333 |
| Accession | MF_01333 |
| Dates | 23-JUN-2004 (Created)
22-SEP-2023 (Last updated, Version 27) |
| Name | Ribosomal_uL5 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | P08895 (RL5_GEOSE); Q9RXJ0 (RL5_DEIRA); P62399 (RL5_ECOLI); P41201 (RL5_THETH); P14124 (RL5_HALMA); Q5SHQ0 (RL5_THET8); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01333_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01333_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL5 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL5; |
| Gene name | Name=rplE; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL5 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL5; |
| Gene name | Name=rplE; Synonyms=rpl5; |
| else case <OC:Archaea> | |
| Identifier | RL5 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL5; |
| Gene name | Name=rpl5; |
| else case <OG:Chloroplast> | |
| Identifier | RK5 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL5c; |
| Gene name | Name=rpl5; |
| end case | |
Comments
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| case <OC:Bacteria> | |
| FUNCTION | This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. |
| SUBUNIT | Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome. |
| else case <OC:Archaea> | |
| FUNCTION | This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. |
| SUBUNIT | Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome. |
| else case <OG:Chloroplast> | |
| FUNCTION | Binds 5S rRNA, forms part of the central protuberance of the 50S subunit. |
| SUBUNIT | Part of the 50S ribosomal subunit; contacts the 5S rRNA. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uL5 family. |
Keywords
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| case <FT:1> | |
| Acetylation | |
| end case | |
| Ribonucleoprotein | |
| Ribosomal protein | |
| RNA-binding | |
| rRNA-binding | |
| case not <OG:Chloroplast> | |
| tRNA-binding | |
| end case | |
Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| case not <OG:Chloroplast> | |
| GO:0000049; Molecular function:tRNA binding | |
| end case | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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Features
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| From: RL5_ECOLI (P62399) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Escherichia> or <OC:Shigella> | ||||||||||||
| MOD_RES | 3 | 3 | /note="N6-acetyllysine" | K | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 165-194 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |