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HAMAP rule MF_01333

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General rule information [?]

Accession MF_01333
Dates 23-JUN-2004 (Created)
12-JUN-2023 (Last updated, Version 26)
Name Ribosomal_L5
Scope
Bacteria
Archaea
Plastid
Templates P08895 (RL5_GEOSE); Q9RXJ0 (RL5_DEIRA); P62399 (RL5_ECOLI); P41201 (RL5_THETH); P14124 (RL5_HALMA); Q5SHQ0 (RL5_THET8): [Recover all]
case <OC:Bacteria> or <OG:Chloroplast>
Triggered by
end case

case <OC:Archaea>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
Identifier
RL5
Protein name
RecName: Full=Large ribosomal subunit protein uL5;
Gene name
rplE
else case <OC:Cyanobacteriota>
Identifier
RL5
Protein name
RecName: Full=Large ribosomal subunit protein uL5;
Gene name
rplE, rpl5
else case <OC:Archaea>
Identifier
RL5
Protein name
RecName: Full=Large ribosomal subunit protein uL5;
Gene name
rpl5
else case <OG:Chloroplast>
Identifier
RK5
Protein name
RecName: Full=Large ribosomal subunit protein uL5c;
Gene name
rpl5
end case

Comments [?]

case <OC:Bacteria>
Function This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
Subunit Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
else case <OC:Archaea>
Function This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
Subunit Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
else case <OG:Chloroplast>
Function Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
Subunit Part of the 50S ribosomal subunit; contacts the 5S rRNA.
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the universal ribosomal protein uL5 family.

Keywords [?]

case <FT:1>
Acetylation
end case
Ribonucleoprotein
Ribosomal protein
RNA-binding
rRNA-binding
case not <OG:Chloroplast>
tRNA-binding
end case

Gene Ontology [?]

GO:0019843; Molecular function: rRNA binding.
case not <OG:Chloroplast>
GO:0000049; Molecular function: tRNA binding.
end case
GO:0006412; Biological process: translation.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF00281; Ribosomal_L5; 1;
PF00673; Ribosomal_L5_C; 1;
PROSITE PS00358; RIBOSOMAL_L5; 1;

Features [?]

case <OC:Escherichia> or <OC:Shigella>
From: RL5_ECOLI (P62399)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     3     3       N6-acetyllysine     K  
end case

Additional information [?]

case <OC:Bacteria>
Size range 177-238 amino acids
end case
case <OC:Archaea>
Size range 165-194 amino acids
end case
Related rules None
Fusion None


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