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HAMAP rule MF_01376

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General rule information [?]

Accession MF_01376
Dates 19-APR-2007 (Created)
1-JUN-2023 (Last updated, Version 25)
Name PhnW_aminotrans_5
Scope(s) Bacteria
Bacteroidota
Bacillota
Pseudomonadota
Template(s) P96060 (PHNW_SALTY); Q9I434 (PHNW_PSEAE); [ Recover all ]
Triggered by HAMAP; MF_01376 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PHNW
Protein name RecName: Full=2-aminoethylphosphonate--pyruvate transaminase;
                 EC=2.6.1.37;
AltName: Full=2-aminoethylphosphonate aminotransferase;
AltName: Full=AEP transaminase;
                 Short=AEPT;
Gene name Name=phnW;

Comments [?]

FUNCTIONInvolved in phosphonate degradation.
CATALYTIC ACTIVITY Reaction=(2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde; Xref=Rhea:RHEA:17021, ChEBI:CHEBI:15361, ChEBI:CHEBI:57418, ChEBI:CHEBI:57972, ChEBI:CHEBI:58383; EC=2.6.1.37;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
SUBUNITHomodimer.
SIMILARITYBelongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.

Keywords [?]


Gene Ontology [?]

GO:0047304; Molecular function:2-aminoethylphosphonate-pyruvate transaminase activity

Cross-references [?]

Pfam PF00266; Aminotran_5; 1;
PROSITE PS00595; AA_TRANSFER_CLASS_5; 1;
NCBIfam TIGR02326; Transamin_PhnW; 1;

Features [?]

From: PHNW_SALTY (P96060)
Key From To Description Tag Condition FTGroup
MOD_RES 194 194 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 269-389 amino acids
Related rules None
Fusion Nter: MF_01375 (phnX) Cter: None
Comments Fused with phnX in CLOD6.



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