HAMAP rule MF_01376
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01376 |
| Accession | MF_01376 |
| Dates | 19-APR-2007 (Created)
02-SEP-2024 (Last updated, Version 27) |
| Name | PhnW_aminotrans_5 |
| Scope(s) |
Bacteria Bacteroidota Bacillota Pseudomonadota |
| Template(s) | P96060; Q9I434; [ Recover all ] |
| Triggered by |
HAMAP; MF_01376 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PHNW |
| Protein name | RecName: Full=2-aminoethylphosphonate--pyruvate transaminase; EC=2.6.1.37; AltName: Full=2-aminoethylphosphonate aminotransferase; AltName: Full=AEP transaminase; Short=AEPT; |
| Gene name | Name=phnW; |
Comments
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| FUNCTION | Involved in phosphonate degradation. |
| CATALYTIC ACTIVITY | Reaction=(2-aminoethyl)phosphonate + pyruvate = phosphonoacetaldehyde + L-alanine; Xref=Rhea:RHEA:17021, ChEBI:CHEBI:15361, ChEBI:CHEBI:57418, ChEBI:CHEBI:57972, ChEBI:CHEBI:58383; EC=2.6.1.37; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. |
Keywords
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Gene Ontology
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| GO:0047304; Molecular function:2-aminoethylphosphonate-pyruvate transaminase activity |
Cross-references
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| Pfam | PF00266; Aminotran_5; 1; |
| PROSITE | PS00595; AA_TRANSFER_CLASS_5; 1; |
| NCBIfam | TIGR02326; Transamin_PhnW; 1; |
Features
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| From: PHNW_SALTY (P96060) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 194 | 194 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 269-389 amino acids |
| Related rules |
None |
| Fusion | Nter: MF_01375 (phnX) Cter: None |
| Comments | Fused with phnX in CLOD6. |