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HAMAP rule MF_01377

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General rule information [?]

Accession MF_01377
Dates 4-JUN-2007 (Created)
1-JUN-2023 (Last updated, Version 23)
Name YegS
Scope(s) Bacteria
Template(s) P76407 (YEGS_ECOLI); Q8ZNP1 (YEGS_SALTY); [ Recover all ]
Triggered by HAMAP; MF_01377 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier YEGS
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Protein name RecName: Full=Probable lipid kinase YegS;
Gene name Name=yegS;
Protein name RecName: Full=Probable lipid kinase YegS-like;
end case

Comments [?]

FUNCTIONProbably phosphorylates lipids; the in vivo substrate is unknown.
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Note=Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.;
SIMILARITYBelongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.

Keywords [?]

Gene Ontology [?]

GO:0000287; Molecular function:magnesium ion binding
GO:0001727; Molecular function:lipid kinase activity
GO:0005524; Molecular function:ATP binding
GO:0008654; Biological process:phospholipid biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00781; DAGK_cat; 1;
NCBIfam TIGR03702; lip_kinase_YegS; 1;
NCBIfam TIGR00147; TIGR00147; 1;

Features [?]

From: YEGS_ECOLI (P76407)
Key From To Description Tag Condition FTGroup
BINDING 66 72 /ligand="ATP"
ACT_SITE 271 271 /note="Proton acceptor" E
BINDING 215 215 /ligand="Mg(2+)"
BINDING 218 218 /ligand="Mg(2+)"
BINDING 220 220 /ligand="Mg(2+)"
BINDING 40 40 /ligand="ATP"
BINDING 95 95 /ligand="ATP"

Additional information [?]

Size range 290-340 amino acids
Related rules None
Fusion Nter: None Cter: None

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