HAMAP rule MF_01385
General rule information
[?]
Accession |
MF_01385 |
Dates |
19-JUN-2008 (Created) 20-MAY-2021 (Last updated, Version 9) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
|
Full=Urease accessory protein UreF;
|
|
Function |
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. |
case not <OC:Helicobacter>
Subunit |
UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. |
else case <OC:Helicobacter>
Subunit |
UreH, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. |
end case
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the UreF family. |
Additional information
[?]
Size range |
205-266 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
For some orally acquired pathogens (Brucella, YERPE) urease acts as a virulence factor. In Brucella there are usually 2 urease operons. |