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Annotation rule MF_01400
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General rule information [?]

Accession MF_01400
Dates 8-APR-2002 (Created)
19-NOV-2019 (Last updated, Version 30)
Name MsrB
Templates P14930 (MSRAB_NEIGO); Q9JWM8 (MSRAB_NEIMA); P0A746 (MSRB_ECOLI); Q3JRF0 (MSRB_BURP1); P0A088 (MSRB_STAA8): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Peptide methionine sulfoxide reductase MsrB;
AltName: Full=Peptide-methionine (R)-S-oxide reductase;
Gene name

Comments [?]

Catalytic activity RHEA:24164: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.
end case
Similarity Belongs to the MsrB Met sulfoxide reductase family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0033743; Molecular function: peptide-methionine (R)-S-oxide reductase activity.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case

Cross-references [?]

Pfam PF01641; SelR; 1;
TIGRFAMs TIGR00357; TIGR00357; 1;
PROSITE PS51790; MSRB; 1; trigger=PRU01126;

Features [?]

From: MSRB_ECOLI (P0A746)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     118     118       Nucleophile     C  
METAL (Optional)     46     46       Zinc     C   1
METAL (Optional)     49     49       Zinc     C   1
METAL (Optional)     95     95       Zinc     C   1
METAL (Optional)     98     98       Zinc     C   1

Additional information [?]

Size range 124-159 amino acids
Related rules None
Fusion Nter: MF_01401 (msrA); Cter: MF_01401 (msrA)