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Annotation rule MF_01415
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General rule information [?]

Accession MF_01415
Dates 2-OCT-2003 (Created)
19-NOV-2019 (Last updated, Version 16)
Name K_H_efflux_KefG
Scope
Bacteria; Gammaproteobacteria
Template P0A756 (KEFG_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KEFG
Protein name
RecName: Full=Glutathione-regulated potassium-efflux system ancillary protein KefG;
AltName: Full=Putative quinone oxidoreductase KefG;
EC 1.6.5.2;
Gene name
kefG

Comments [?]

Function Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
Catalytic activity RHEA:46160: a quinone + H(+) + NADH = a quinol + NAD(+)
EC 1.6.5.2
RHEA:46164: a quinone + H(+) + NADPH = a quinol + NADP(+)
EC 1.6.5.2
Subunit Interacts with KefB.
Subcellular location Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Similarity Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003955; Molecular function: NAD(P)H dehydrogenase (quinone) activity.
GO:0032414; Biological process: positive regulation of ion transmembrane transporter activity.
GO:1901381; Biological process: positive regulation of potassium ion transmembrane transport.

Cross-references [?]

Pfam PF02525; Flavodoxin_2; 1;

Additional information [?]

Size range 175-233 amino acids
Related rules None
Fusion None
Comments KefF is the ancillary protein of KefC, whereas KefG is the ancillary protein of KefB. KefF and KefG cannot complement each other and are specific for their respective efflux system.