HAMAP rule MF_01440

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01440
Accession	MF_01440
Dates	06-SEP-2006 (Created) 02-SEP-2024 (Last updated, Version 21)
Name	CheD
Scope(s)	Bacteria Archaea
Template(s)	P40404; Q9X005; [ Recover all ]
Triggered by	HAMAP; MF_01440 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CHED
case <OC:Bacillus>
Protein name	RecName: Full=Chemoreceptor glutamine deamidase CheD; EC=3.5.1.44;
else
Protein name	RecName: Full=Probable chemoreceptor glutamine deamidase CheD; EC=3.5.1.44;
end case
Gene name	Name=cheD;

Comments [?]

case <OC:Bacillus>
FUNCTION	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the cheA kinase.
CATALYTIC ACTIVITY	Reaction=L-glutaminyl-[protein] + H2O = L-glutamyl-[protein] + NH4(+); Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973, ChEBI:CHEBI:30011; EC=3.5.1.44;
SUBUNIT	Forms a complex with CheC.
else
FUNCTION	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
CATALYTIC ACTIVITY	Reaction=L-glutaminyl-[protein] + H2O = L-glutamyl-[protein] + NH4(+); Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973, ChEBI:CHEBI:30011; EC=3.5.1.44;
end case
SIMILARITY	Belongs to the CheD family.

Keywords [?]

Gene Ontology [?]

GO:0050568; Molecular function:protein-glutamine glutaminase activity

GO:0006935; Biological process:chemotaxis

Cross-references [?]

Pfam	PF03975; CheD; 1;

Features [?]

Additional information [?]