HAMAP rule MF_01463
General rule information
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Accession | MF_01463 |
Dates | 5-JUL-2011 (Created)
1-JUN-2023 (Last updated, Version 10) |
Name | SecD |
Scope(s) |
Bacteria Archaea |
Template(s) | P0AG90 (SECD_ECOLI); Q5SKE6 (SECDF_THET8); E9RGS3 (SECD_VIBAL); D4GTK5 (SECD_HALVD); O32047 (SECDF_BACSU); [ Recover all ] |
Triggered by |
case c? <OC:Bacteria>
HAMAP; MF_01463_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01463_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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Identifier | SECD |
case <OC:Bacteria> | |
RecName: Full=Protein translocase subunit SecD; | |
else case <OC:Archaea> | |
Protein name | RecName: Full=Protein-export membrane protein SecD; |
end case | |
Gene name | Name=secD; |
Comments
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case <OC:Bacteria> | |
FUNCTION | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. |
else case <OC:Archaea> | |
FUNCTION | Involved in protein export. |
end case | |
case <OC:Cyanobacteriota> and not <OC:Gloeobacter> | |
FUNCTION | Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells. |
end case | |
case <OC:Pseudomonadota> | |
SUBUNIT | Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC. |
else case <OC:Bacteria> | |
SUBUNIT | Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved. |
else case <OC:Archaea> | |
SUBUNIT | Part of the protein translocation apparatus. Forms a complex with SecF. |
end case | |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the SecD/SecF family. SecD subfamily. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Membrane | |
Protein transport | |
Translocation | |
Transmembrane | |
Transmembrane helix | |
Transport |
Gene Ontology
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GO:0065002; Biological process:intracellular protein transmembrane transport | |
GO:0006605; Biological process:protein targeting | |
case <OCellular component:Bacteria> | |
GO:0043952; Biological process:protein transport by the Sec complex | |
end case | |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF07549; Sec_GG; 1; |
Pfam | PF02355; SecD_SecF; 1; |
PRINTS | PR01755; SECFTRNLCASE; 1; |
NCBIfam | TIGR00916; 2A0604s01; 1; |
NCBIfam | TIGR01129; SecD; 1; |
General | Transmembrane; -; 6; |
Features
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Additional information
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Size range | 385-570 amino acids |
Related rules |
MF_01464 |
Fusion | Nter: None Cter: MF_01464 (SecF) |
Comments | Often found as a SecDF fusion protein. In bacteria the operon consists of secDF. Some archaea have a secFD operon, in others the genes are separated on the genome. |