HAMAP rule MF_01469

General rule information [?]

Accession	MF_01469
Dates	28-FEB-2012 (Created) 1-JUN-2023 (Last updated, Version 11)

Name

RNase_M5

Scope

Bacteria; Bacillota

Bacteria; Fusobacteriota

Bacteria; Borrelia

Bacteria; Mycoplasmatota

Template

P37547 (RNM5_BACSU)

Triggered by

HAMAP; MF_01469 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RNM5

Protein name

RecName:		Full=Ribonuclease M5;
		EC 3.1.26.8;
AltName:		Full=RNase M5;
AltName:		Full=Ribosomal RNA terminal maturase M5;

Gene name

rnmV

Comments [?]

Function	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
Catalytic activity	Reaction=Endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.; EC=3.1.26.8;
Subcellular location	Cytoplasm.
Similarity	Belongs to the ribonuclease M5 family.

Keywords [?]

Cytoplasm
Endonuclease
Hydrolase
Nuclease
Ribosome biogenesis
RNA-binding
rRNA processing
rRNA-binding

Gene Ontology [?]

GO:0043822; Molecular function: ribonuclease M5 activity.
GO:0006364; Biological process: rRNA processing.
GO:0042254; Biological process: ribosome biogenesis.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01751; Toprim; 1;
PRINTS	PR00418; TPI2FAMILY; 1;
PROSITE	PS50880; TOPRIM; 1; trigger=PRU00995;
NCBIfam	TIGR00334; 5S_RNA_mat_M5; 1;
	TIGR00125; Cyt_tran_rel; 1;

Additional information [?]

Size range	174-227 amino acids
Related rules	None
Fusion	None

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