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HAMAP rule MF_01469

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General rule information [?]

Accession MF_01469
Dates 28-FEB-2012 (Created)
1-JUN-2023 (Last updated, Version 11)
Name RNase_M5
Scope(s) Bacteria
Bacillota
Fusobacteriota
Borrelia
Mycoplasmatota
Template(s) P37547 (RNM5_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01469 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RNM5
Protein name RecName: Full=Ribonuclease M5;
                 EC=3.1.26.8;
AltName: Full=RNase M5;
AltName: Full=Ribosomal RNA terminal maturase M5;
Gene name Name=rnmV;

Comments [?]

FUNCTIONRequired for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
CATALYTIC ACTIVITY Reaction=Endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.; EC=3.1.26.8;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the ribonuclease M5 family.

Keywords [?]


Gene Ontology [?]

GO:0043822; Molecular function:ribonuclease M5 activity
GO:0006364; Biological process:rRNA processing
GO:0042254; Biological process:ribosome biogenesis
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01751; Toprim; 1;
PRINTS PR00418; TPI2FAMILY; 1;
PROSITE PS50880; TOPRIM; 1;
NCBIfam TIGR00334; 5S_RNA_mat_M5; 1;
NCBIfam TIGR00125; Cyt_tran_rel; 1;

Features [?]


Additional information [?]

Size range 174-227 amino acids
Related rules None
Fusion Nter: None Cter: None



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