HAMAP rule MF_01473
General rule information
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Accession | MF_01473 |
Dates | 14-JUN-2012 (Created) 13-JAN-2023 (Last updated, Version 9) |
Name | GtfB |
Scope | Bacteria; Bacillota |
Templates | A0A0H2UR90 (GTFB_STRPN); A1C3M0 (GTFB_STRPA); Q3S2Y1 (GTFB_STRAG); Q79T00 (GTFB_STRGN): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own. |
Pathway | Protein modification; protein glycosylation. |
Subunit | Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus. |
Subcellular location | Cell membrane; Peripheral membrane protein. |
Similarity | Belongs to the GtfB family. |
Keywords
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Gene Ontology
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GO:0017122; Cellular component: protein N-acetylglucosaminyltransferase complex.
GO:0031647; Biological process: regulation of protein stability.
GO:0005886; Cellular component: plasma membrane.
GO:0031647; Biological process: regulation of protein stability.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Additional information
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Size range | 404-466 amino acids |
Related rules | None |
Fusion | None |