HAMAP rule MF_01489
General rule information
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Accession | MF_01489 |
Dates | 24-MAR-2014 (Created)
11-JAN-2024 (Last updated, Version 6) |
Name | Helicase_Rad25_arch |
Scope(s) |
Archaea |
Template(s) | None (); [ Recover all ] |
Triggered by |
HAMAP; MF_01489 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | RAD25 |
RecName: Full=Putative DNA 3'-5' helicase Rad25;<br /> EC=<a href="https://enzyme.expasy.org/EC/5.6.2.4">5.6.2.4</a>; | |
Gene name | Name=rad25; |
Comments
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CATALYTIC ACTIVITY | Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.; EC=5.6.2.4; |
CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4; |
SIMILARITY | Belongs to the helicase family. RAD25/XPB subfamily. |
Keywords
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ATP-binding | |
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a> | |
Hydrolase | |
Isomerase | |
Nucleotide-binding |
Gene Ontology
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GO:0005524; Molecular function:ATP binding |
GO:0004386; Molecular function:helicase activity |
GO:0016818; Molecular function:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
Cross-references
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PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
PROSITE | PS51194; HELICASE_CTER; 1; |
Pfam | PF00271; Helicase_C; 1; |
Features
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Additional information
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Size range | 540-730 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |